PDB entry 5hvw

View 5hvw on RCSB PDB site
Description: Monomeric IgG4 Fc
Class: immune system
Keywords: Biotechnology, antibody engineering, monomeric Fc, monovalent targeting, fusion protein, IMMUNE SYSTEM
Deposited on 2016-01-28, released 2016-08-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ig gamma-4 chain c region
    Species: Homo sapiens [TaxId:9606]
    Gene: IGHG4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01861 (0-209)
      • engineered mutation (116)
      • engineered mutation (131)
      • engineered mutation (160)
      • engineered mutation (170)
      • engineered mutation (172)
    Domains in SCOPe 2.08: d5hvwa1, d5hvwa2
  • Heterogens: ZN, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5hvwA (A:)
lggpsvflfppkpkdtlmisrtpevtcvvvdvsqedpevqfnwyvdgvevhnaktkpree
qfnstyrvvsvltvlhqdwlngkeykckvsnkglpssiektiskakgqprepqvytfpps
qeemtknqvslrclvkgfypsdiavewesngqpennykttkpvldsdgsfrlesrltvdk
srwqegnvfscsvmhealhnhytqkslsls