PDB entry 5hvt
View 5hvt on RCSB PDB site
Description: Crystal Structure of Macrophage Migration Inhibitory Factor (MIF) with a Potent Inhibitor (NVS-2)
Class: ISOMERASE/ISOMERASE inhibitor
Keywords: Cytokine, Inhibitor, Complex, ISOMERASE-ISOMERASE inhibitor complex
Deposited on
2016-01-28, released
2016-06-29
The last revision prior to the SCOPe 2.08 freeze date was dated
2016-07-20, with a file datestamp of
2016-07-15.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: N/A
AEROSPACI score: 0.39
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: macrophage migration inhibitory factor
Species: Homo sapiens [TaxId:9606]
Gene: MIF, GLIF, MMIF
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5hvta_ - Chain 'B':
Compound: macrophage migration inhibitory factor
Species: Homo sapiens [TaxId:9606]
Gene: MIF, GLIF, MMIF
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5hvtb_ - Chain 'C':
Compound: macrophage migration inhibitory factor
Species: Homo sapiens [TaxId:9606]
Gene: MIF, GLIF, MMIF
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5hvtc_ - Heterogens: SO4, NVS, GOL, IPA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>5hvtA (A:)
pmfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
lhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>5hvtB (B:)
pmfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
lhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa
- Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)
>5hvtC (C:)
pmfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
lhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa