PDB entry 5f6h

View 5f6h on RCSB PDB site
Description: Crystal Structure of Tier 2 Neutralizing Antibody DH427 from a Rhesus Macaque
Class: immune system
Keywords: fab fragment, hiv-1, antibody, immune system
Deposited on 2015-12-06, released 2016-01-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-09-27, with a file datestamp of 2017-09-22.
Experiment type: XRAY
Resolution: 2.66 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'I':
    Compound: DH427 Antibody Heavy Chain
    Species: MACACA MULATTA [TaxId:9544]
    Database cross-references and differences (RAF-indexed):
    • PDB 5F6H (0-End)
    Domains in SCOPe 2.08: d5f6hi_
  • Chain 'J':
    Compound: DH427 Antibody Light Chain
    Species: MACACA MULATTA [TaxId:9544]
    Database cross-references and differences (RAF-indexed):
    • PDB 5F6H
    Domains in SCOPe 2.08: d5f6hj1, d5f6hj2
  • Chain 'K':
    Compound: DH427 Antibody Heavy Chain
    Species: MACACA MULATTA [TaxId:9544]
    Database cross-references and differences (RAF-indexed):
    • PDB 5F6H (0-End)
    Domains in SCOPe 2.08: d5f6hk_
  • Chain 'L':
    Compound: DH427 Antibody Light Chain
    Species: MACACA MULATTA [TaxId:9544]
    Database cross-references and differences (RAF-indexed):
    • PDB 5F6H
    Domains in SCOPe 2.08: d5f6hl1, d5f6hl2
  • Chain 'M':
    Compound: DH427 Antibody Heavy Chain
    Species: MACACA MULATTA [TaxId:9544]
    Database cross-references and differences (RAF-indexed):
    • PDB 5F6H (0-End)
    Domains in SCOPe 2.08: d5f6hm_
  • Chain 'N':
    Compound: DH427 Antibody Light Chain
    Species: MACACA MULATTA [TaxId:9544]
    Database cross-references and differences (RAF-indexed):
    • PDB 5F6H
    Domains in SCOPe 2.08: d5f6hn1, d5f6hn2
  • Chain 'O':
    Compound: DH427 Antibody Heavy Chain
    Species: MACACA MULATTA [TaxId:9544]
    Database cross-references and differences (RAF-indexed):
    • PDB 5F6H (0-End)
    Domains in SCOPe 2.08: d5f6ho_
  • Chain 'P':
    Compound: DH427 Antibody Light Chain
    Species: MACACA MULATTA [TaxId:9544]
    Database cross-references and differences (RAF-indexed):
    • PDB 5F6H
    Domains in SCOPe 2.08: d5f6hp1, d5f6hp2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >5f6hI (I:)
evqlvesggglvqpggslrlscaasgftfsnsgmiwvrqapgkglewvsyislsgantyy
adsvkgrftisrdnsqntlslqmnslrvedtamyycakegwsyfdfwgqgvlvtvsgast
kgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
slssvvtvpssslgtqtyicnvnhkpsntkvdkrvepscdkhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5f6hI (I:)
evqlvesggglvqpggslrlscaasgftfsnsgmiwvrqapgkglewvsyislsgantyy
adsvkgrftisrdnsqntlslqmnslrvedtamyycakegwsyfdfwgqgvlvtvsgast
kgpsvfplapgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvvt
vpssslgtqtyicnvnhkpsntkvdkrvep

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >5f6hJ (J:)
qsaltqppsvskslgqsvtisctgtssdigaytgvswyqqhsgtaprlliydvskrpsgv
sdrfsgsksgntasltisglqtddeadyyccsyrtgatyifgtgtrvtvlgqpkgapsvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >5f6hJ (J:)
saltqppsvskslgqsvtisctgtssdigaytgvswyqqhsgtaprlliydvskrpsgvs
drfsgsksgntasltisglqtddeadyyccsyrtgatyifgtgtrvtvlgqpkgapsvtl
fppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassy
lsltpeqwkshrsyscqvthegstvektvapt

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >5f6hK (K:)
evqlvesggglvqpggslrlscaasgftfsnsgmiwvrqapgkglewvsyislsgantyy
adsvkgrftisrdnsqntlslqmnslrvedtamyycakegwsyfdfwgqgvlvtvsgast
kgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
slssvvtvpssslgtqtyicnvnhkpsntkvdkrvepscdkhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5f6hK (K:)
evqlvesggglvqpggslrlscaasgftfsnsgmiwvrqapgkglewvsyislsgantyy
adsvkgrftisrdnsqntlslqmnslrvedtamyycakegwsyfdfwgqgvlvtvsgast
kgpsvfplapgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvvt
vpssslgtqtyicnvnhkpsntkvdkrvep

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >5f6hL (L:)
qsaltqppsvskslgqsvtisctgtssdigaytgvswyqqhsgtaprlliydvskrpsgv
sdrfsgsksgntasltisglqtddeadyyccsyrtgatyifgtgtrvtvlgqpkgapsvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >5f6hL (L:)
saltqppsvskslgqsvtisctgtssdigaytgvswyqqhsgtaprlliydvskrpsgvs
drfsgsksgntasltisglqtddeadyyccsyrtgatyifgtgtrvtvlgqpkgapsvtl
fppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassy
lsltpeqwkshrsyscqvthegstvektvapt

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >5f6hM (M:)
evqlvesggglvqpggslrlscaasgftfsnsgmiwvrqapgkglewvsyislsgantyy
adsvkgrftisrdnsqntlslqmnslrvedtamyycakegwsyfdfwgqgvlvtvsgast
kgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
slssvvtvpssslgtqtyicnvnhkpsntkvdkrvepscdkhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5f6hM (M:)
evqlvesggglvqpggslrlscaasgftfsnsgmiwvrqapgkglewvsyislsgantyy
adsvkgrftisrdnsqntlslqmnslrvedtamyycakegwsyfdfwgqgvlvtvsgast
kgpsvfplapgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvvt
vpssslgtqtyicnvnhkpsntkvdkrvep

  • Chain 'N':
    Sequence, based on SEQRES records: (download) 
    >5f6hN (N:)
qsaltqppsvskslgqsvtisctgtssdigaytgvswyqqhsgtaprlliydvskrpsgv
sdrfsgsksgntasltisglqtddeadyyccsyrtgatyifgtgtrvtvlgqpkgapsvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >5f6hN (N:)
saltqppsvskslgqsvtisctgtssdigaytgvswyqqhsgtaprlliydvskrpsgvs
drfsgsksgntasltisglqtddeadyyccsyrtgatyifgtgtrvtvlgqpkgapsvtl
fppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassy
lsltpeqwkshrsyscqvthegstvektvapt

  • Chain 'O':
    Sequence, based on SEQRES records: (download) 
    >5f6hO (O:)
evqlvesggglvqpggslrlscaasgftfsnsgmiwvrqapgkglewvsyislsgantyy
adsvkgrftisrdnsqntlslqmnslrvedtamyycakegwsyfdfwgqgvlvtvsgast
kgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
slssvvtvpssslgtqtyicnvnhkpsntkvdkrvepscdkhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5f6hO (O:)
evqlvesggglvqpggslrlscaasgftfsnsgmiwvrqapgkglewvsyislsgantyy
adsvkgrftisrdnsqntlslqmnslrvedtamyycakegwsyfdfwgqgvlvtvsgast
kgpsvfplapgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvvt
vpssslgtqtyicnvnhkpsntkvdkrvep

  • Chain 'P':
    Sequence, based on SEQRES records: (download) 
    >5f6hP (P:)
qsaltqppsvskslgqsvtisctgtssdigaytgvswyqqhsgtaprlliydvskrpsgv
sdrfsgsksgntasltisglqtddeadyyccsyrtgatyifgtgtrvtvlgqpkgapsvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >5f6hP (P:)
saltqppsvskslgqsvtisctgtssdigaytgvswyqqhsgtaprlliydvskrpsgvs
drfsgsksgntasltisglqtddeadyyccsyrtgatyifgtgtrvtvlgqpkgapsvtl
fppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassy
lsltpeqwkshrsyscqvthegstvektvapt