PDB entry 5djm

View 5djm on RCSB PDB site
Description: Structure of WT Human Glutathione Transferase in complex with cisplatin in the absence of glutathione.
Class: transferase/transferase inhibitor
Keywords: Anticancer Cisplatin, transferase-transferase inhibitor complex
Deposited on 2015-09-02, released 2016-11-02
The last revision prior to the SCOPe 2.06 freeze date was dated 2016-11-02, with a file datestamp of 2016-10-28.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutathione S-transferase P
    Species: Homo sapiens [TaxId:9606]
    Gene: GSTP1, FAEES3, GST3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5djma1, d5djma2
  • Chain 'B':
    Compound: Glutathione S-transferase P
    Species: Homo sapiens [TaxId:9606]
    Gene: GSTP1, FAEES3, GST3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5djmb1, d5djmb2
  • Heterogens: MES, PT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5djmA (A:)
mppytvvyfpvrgrcaalrmlladqgqswkeevvtvetwqegslkasclygqlpkfqdgd
ltlyqsntilrhlgrtlglygkdqqeaalvdmvndgvedlrckyisliytnyeagkddyv
kalpgqlkpfetllsqnqggktfivgdqisfadynlldlllihevlapgcldafpllsay
vgrlsarpklkaflaspeyvnlpingngkq

    Sequence, based on observed residues (ATOM records): (download) 
    >5djmA (A:)
ppytvvyfpvrgrcaalrmlladqgqswkeevvtvsclygqlpkfqdgdltlyqsntilr
hlgrtlglygkdqqeaalvdmvndgvedlrckyisliytnyeagkddyvkalpgqlkpfe
tllsqnqggktfivgdqisfadynlldlllihevlapgcldafpllsayvgrlsarpklk
aflaspeyvnlpingngkq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5djmB (B:)
mppytvvyfpvrgrcaalrmlladqgqswkeevvtvetwqegslkasclygqlpkfqdgd
ltlyqsntilrhlgrtlglygkdqqeaalvdmvndgvedlrckyisliytnyeagkddyv
kalpgqlkpfetllsqnqggktfivgdqisfadynlldlllihevlapgcldafpllsay
vgrlsarpklkaflaspeyvnlpingngkq

    Sequence, based on observed residues (ATOM records): (download) 
    >5djmB (B:)
pytvvyfpvrgrcaalrmlladqgqswkeevvtwclygqlpkfqdgdltlyqsntilrhl
grtlglygkdqqeaalvdmvndgvedlrckyisliytnyeagkddyvkalpgqlkpfetl
lsqnqggktfivgdqisfadynlldlllihevlapgcldafpllsayvgrlsarpklkaf
laspeyvnlpingngkq