PDB entry 5cfp

View 5cfp on RCSB PDB site
Description: Crystal structure of anemone STING (Nematostella vectensis) 'humanized' F276K in complex with 3', 3' c-di-GMP, c[G(3', 5')pG(3', 5')p]'
Class: immune system
Keywords: STING, cyclic-dinucleotide binding domain, IMMUNE SYSTEM
Deposited on 2015-07-08, released 2015-08-26
The last revision prior to the SCOPe 2.05 freeze date was dated 2015-08-26, with a file datestamp of 2015-08-21.
Experiment type: XRAY
Resolution: 2.07 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Stimulator of Interferon Genes
    Species: Nematostella vectensis [TaxId:45351]
    Gene: v1g246111
    Database cross-references and differences (RAF-indexed):
    • Uniprot A7SLZ2
      • engineered mutation (100)
    Domains in SCOPe 2.05: d5cfpa_
  • Chain 'B':
    Compound: Stimulator of Interferon Genes
    Species: Nematostella vectensis [TaxId:45351]
    Gene: v1g246111
    Database cross-references and differences (RAF-indexed):
    • Uniprot A7SLZ2
      • engineered mutation (100)
    Domains in SCOPe 2.05: d5cfpb_
  • Heterogens: C2E, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5cfpA (A:)
gslskveesqlnekenknvadglawsyyfgylkfvlpelekqiektskfrskekfvkkmf
ilipsncfwddkipgsdydpqnritfegnteplektrggvklrhykhsvyeikdgenepw
fcimeyatplltlydmsvaqpgelsreerdaqvvvflrklqdilegdracqgkyelvtfs
pdrdladvmlrklkdseleigg

    Sequence, based on observed residues (ATOM records): (download) 
    >5cfpA (A:)
knvadglawsyyfgylkfvlpelekqiektskfrskekfvkkmfilipsncfwddkipgs
dydpqnritfegnteplektrggvklrhykhsvyeikdgenepwfcimeyatplltlydm
svaqpgelsreerdaqvvvflrklqdilegdracqgkyelvtfspdrdladvmlrklkds
e

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5cfpB (B:)
gslskveesqlnekenknvadglawsyyfgylkfvlpelekqiektskfrskekfvkkmf
ilipsncfwddkipgsdydpqnritfegnteplektrggvklrhykhsvyeikdgenepw
fcimeyatplltlydmsvaqpgelsreerdaqvvvflrklqdilegdracqgkyelvtfs
pdrdladvmlrklkdseleigg

    Sequence, based on observed residues (ATOM records): (download) 
    >5cfpB (B:)
knvadglawsyyfgylkfvlpelekqiektskfrskekfvkkmfilipsncfwddkipgs
dydpqnritfegnteplektrggvklrhykhsvyeikdgenepwfcimeyatplltlydm
svaqpgelsreerdaqvvvflrklqdilegdracqgkyelvtfspdrdladvmlrklkds
e