PDB entry 4ywi

View 4ywi on RCSB PDB site
Description: F96S/L167V Double mutant of Plasmodium Falciparum Triosephosphate Isomerase
Class: isomerase
Keywords: tim barrels, beta-alpha barrels, isomerase, glycolysis
Deposited on 2015-03-20, released 2016-02-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-04-20, with a file datestamp of 2016-04-15.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: triosephosphate isomerase
    Species: Plasmodium falciparum [TaxId:5833]
    Gene: tpi
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07412 (Start-247)
      • engineered mutation (95)
      • engineered mutation (162)
      • engineered mutation (166)
    Domains in SCOPe 2.08: d4ywia_
  • Chain 'B':
    Compound: triosephosphate isomerase
    Species: Plasmodium falciparum [TaxId:5833]
    Gene: tpi
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07412 (Start-247)
      • engineered mutation (95)
      • engineered mutation (162)
      • engineered mutation (166)
    Domains in SCOPe 2.08: d4ywib_
  • Heterogens: SO4, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ywiA (A:)
markyfvaanwkcngtlesiksltnsfnnldfdpskldvvvfpvsvhydhtrkllqskfs
tgiqnvskfgngsytgevsaeiakdlnieyviighserrkyfhetdedvreklqaslknn
lkavvcfgesleqreqnktievitkqvkafvdlidnfdnvilvyepvwaigtgktatpeq
aqlvhkeirkivkdtcgekqanqirilyggsvntencssliqqedidgflvgnaslkesf
vdiiksam

    Sequence, based on observed residues (ATOM records): (download) 
    >4ywiA (A:)
arkyfvaanwkcngtlesiksltnsfnnldfdpskldvvvfpvsvhydhtrkllqskfst
giqnvskfgngsytgevsaeiakdlnieyviighserrkyfhetdedvreklqaslknnl
kavvcfgesleqreqnktievitkqvkafvdlidnfdnvilvyepvwaitgktatpeqaq
lvhkeirkivkdtcgekqanqirilyggsvntencssliqqedidgflvgnaslkesfvd
iiksam

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4ywiB (B:)
markyfvaanwkcngtlesiksltnsfnnldfdpskldvvvfpvsvhydhtrkllqskfs
tgiqnvskfgngsytgevsaeiakdlnieyviighserrkyfhetdedvreklqaslknn
lkavvcfgesleqreqnktievitkqvkafvdlidnfdnvilvyepvwaigtgktatpeq
aqlvhkeirkivkdtcgekqanqirilyggsvntencssliqqedidgflvgnaslkesf
vdiiksam

    Sequence, based on observed residues (ATOM records): (download) 
    >4ywiB (B:)
arkyfvaanwkcngtlesiksltnsfnnldfdpskldvvvfpvsvhydhtrkllqskfst
giqnvskfgngsytgevsaeiakdlnieyviighserrkyfhetdedvreklqaslknnl
kavvcfgesleqreqnktievitkqvkafvdlidnfdnvilvyepvwaigtgktatpeqa
qlvhkeirkivkdtcgekqanqirilyggsvntencssliqqedidgflvgnaslkesfv
diiksam