PDB entry 4xxv

View 4xxv on RCSB PDB site
Description: Crystal structure of 3-isopropylmalate dehydrogenase from Burkholderia thailandensis in complex with NAD
Class: oxidoreductase
Keywords: SSGCID, 3-isopropylmalate dehydrogenase, NAD, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, OXIDOREDUCTASE
Deposited on 2015-01-31, released 2015-02-25
The last revision prior to the SCOPe 2.05 freeze date was dated 2015-02-25, with a file datestamp of 2015-02-20.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.15
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-isopropylmalate dehydrogenase
    Species: Burkholderia thailandensis [TaxId:271848]
    Gene: leuB, BTH_II0674
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2T7H6 (8-362)
      • expression tag (7)
    Domains in SCOPe 2.05: d4xxva_
  • Chain 'B':
    Compound: 3-isopropylmalate dehydrogenase
    Species: Burkholderia thailandensis [TaxId:271848]
    Gene: leuB, BTH_II0674
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4xxvb_
  • Heterogens: NAD, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4xxvA (A:)
mahhhhhhmkiavlpgdgigpeivneavkvlnaldekfelehapvggagyeasghplpda
tlalakeadailfgavgdwkydsleralrpeqailglrkhlelfanfrpaicypqlvdas
plkpelvagldilivrelngdiyfgqprgvraapdgpfageregfdtmrysepevrriah
vafqaaqkrakkllsvdksnvletsqfwrdvmidvskeyadvelshmyvdnaamqlakap
kqfdvivtgnmfgdilsdeasmltgsigmlpsasldknnkglyepshgsapdiagkgian
platilsaamllryslnraeqadrieravktvleqgyrtgdiatpgcrqvgtaamgdavv
aal

    Sequence, based on observed residues (ATOM records): (download) 
    >4xxvA (A:)
hmkiavlpgdgigpeivneavkvlnaldekfelehapvggagyeasghplpdatlalake
adailfgavgdwkydsleralrpeqailglrkhlelfanfrpaicypqlvdasplkpelv
agldilivrelngdiyfgqprgvraapdgpfageregfdtmrysepevrriahvafqaaq
krakkllsvdksnvletsqfwrdvmidvskeyadvelshmyvdnaamqlakapkqfdviv
tgnmfgdilsdeasmltgsigmlpsasldknnkglyepshgsapdiagkgianplatils
aamllryslnraeqadrieravktvleqgyrtgdiatpgcrqvgtaamgdavvaal

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4xxvB (B:)
mahhhhhhmkiavlpgdgigpeivneavkvlnaldekfelehapvggagyeasghplpda
tlalakeadailfgavgdwkydsleralrpeqailglrkhlelfanfrpaicypqlvdas
plkpelvagldilivrelngdiyfgqprgvraapdgpfageregfdtmrysepevrriah
vafqaaqkrakkllsvdksnvletsqfwrdvmidvskeyadvelshmyvdnaamqlakap
kqfdvivtgnmfgdilsdeasmltgsigmlpsasldknnkglyepshgsapdiagkgian
platilsaamllryslnraeqadrieravktvleqgyrtgdiatpgcrqvgtaamgdavv
aal

    Sequence, based on observed residues (ATOM records): (download) 
    >4xxvB (B:)
mkiavlpgdgigpeivneavkvlnaldekfelehapvggagyeasghplpdatlalakea
dailfgavgdwkydsleralrpeqailglrkhlelfanfrpaicypqlvdasplkpelva
gldilivrelngdiyfgqprgvraapdgpfageregfdtmrysepevrriahvafqaaqk
rakkllsvdksnvletsqfwrdvmidvskeyadvelshmyvdnaamqlakapkqfdvivt
gnmfgdilsdeasmltgsigmlpsasldknnkglyepshgsapdiagkgianplatilsa
amllryslnraeqadrieravktvleqgyrtgdiatpgcrqvgtaamgdavvaal