PDB entry 4xau

View 4xau on RCSB PDB site
Description: Crystal structure of AtS13 from Actinomadura melliaura
Class: transferase
Keywords: sugar aminotransferase, Structural Genomics, PSI-2, Protein Structure Initiative, Enzyme Discovery for Natural Product Biosynthesis, NatPro, TRANSFERASE
Deposited on 2014-12-15, released 2014-12-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-25, with a file datestamp of 2019-12-20.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Putative aminotransferase
    Species: Actinomadura melliaura [TaxId:360723]
    Gene: atS13
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q0H2X1 (20-388)
      • expression tag (17-19)
    Domains in SCOPe 2.08: d4xaua1, d4xaua2
  • Chain 'B':
    Compound: Putative aminotransferase
    Species: Actinomadura melliaura [TaxId:360723]
    Gene: atS13
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q0H2X1 (20-388)
      • expression tag (11-19)
    Domains in SCOPe 2.08: d4xaub1, d4xaub2
  • Chain 'C':
    Compound: Putative aminotransferase
    Species: Actinomadura melliaura [TaxId:360723]
    Gene: atS13
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q0H2X1 (20-388)
      • expression tag (15-19)
    Domains in SCOPe 2.08: d4xauc1, d4xauc2
  • Chain 'D':
    Compound: Putative aminotransferase
    Species: Actinomadura melliaura [TaxId:360723]
    Gene: atS13
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q0H2X1 (20-388)
      • expression tag (11-19)
    Domains in SCOPe 2.08: d4xaud1, d4xaud2
  • Chain 'E':
    Compound: Putative aminotransferase
    Species: Actinomadura melliaura [TaxId:360723]
    Gene: atS13
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q0H2X1 (20-388)
      • expression tag (16-19)
    Domains in SCOPe 2.08: d4xaue1, d4xaue2
  • Chain 'F':
    Compound: Putative aminotransferase
    Species: Actinomadura melliaura [TaxId:360723]
    Gene: atS13
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q0H2X1 (20-388)
      • expression tag (16-19)
    Domains in SCOPe 2.08: d4xauf1, d4xauf2
  • Chain 'G':
    Compound: Putative aminotransferase
    Species: Actinomadura melliaura [TaxId:360723]
    Gene: atS13
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q0H2X1 (20-388)
      • expression tag (16-19)
    Domains in SCOPe 2.08: d4xaug1, d4xaug2
  • Heterogens: PLP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4xauA (A:)
mgsshhhhhhssglvprgshmiplfkvavsptaldrvaevfasgylgqgprvaefesala
arlgnprvvsvhsgtsglclalrlldapeerdevlstpltfeatnwailadgrritwvdv
dpatltmdlddlerkispatraiivvhwtgypvdldrlagildraerehgfrpaviedca
hawgasyrgvplgshgnmcvfsfqalkhltcgdgglltlpgdelheramlrrfygidrta
drlrgaydvaewglkwhmtdlnaaiglanletvdeqlrlhrenaafydkeltgvpglell
qrspdregsfyvydvkvddrpafhrkmeaagimaglvsrrndehscvahlrtslpgldsv
ydrmvslpvgwwlteqdrehvvatirsgw

    Sequence, based on observed residues (ATOM records): (download) 
    >4xauA (A:)
gshmiplfkvavsptaldrvaevfasgylgqgprvaefesalaarlgnprvvsvhsgtsg
lclalrlldapeerdevlstpltfeatnwailadgrritwvdvdpatltmdlddlerkis
patraiivvhwtgypvdldrlagildraerehgfrpaviedcahawgasyrgvplgshgn
mcvfsfqalkhltcgdgglltlpgdelheramlrrfygidrtadrlrgaydvaewglkwh
mtdlnaaiglanletvdeqlrlhrenaafydkeltgvpglellqrspdregsfyvydvkv
ddrpafhrkmeaagimaglvsrrndehscvahlrtslpgldsvydrmvslpvgwwlteqd
rehvvatirsgw

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4xauB (B:)
mgsshhhhhhssglvprgshmiplfkvavsptaldrvaevfasgylgqgprvaefesala
arlgnprvvsvhsgtsglclalrlldapeerdevlstpltfeatnwailadgrritwvdv
dpatltmdlddlerkispatraiivvhwtgypvdldrlagildraerehgfrpaviedca
hawgasyrgvplgshgnmcvfsfqalkhltcgdgglltlpgdelheramlrrfygidrta
drlrgaydvaewglkwhmtdlnaaiglanletvdeqlrlhrenaafydkeltgvpglell
qrspdregsfyvydvkvddrpafhrkmeaagimaglvsrrndehscvahlrtslpgldsv
ydrmvslpvgwwlteqdrehvvatirsgw

    Sequence, based on observed residues (ATOM records): (download) 
    >4xauB (B:)
sglvprgshmiplfkvavsptaldrvaevfasgylgqgprvaefesalaarlgnprvvsv
hsgtsglclalrlldapeerdevlstpltfeatnwailadgrritwvdvdpatltmdldd
lerkispatraiivvhwtgypvdldrlagildraerehgfrpaviedcahawgasyrgvp
lgshgnmcvfsfqalkhltcgdgglltlpgdelheramlrrfygidrtadrlrgaydvae
wglkwhmtdlnaaiglanletvdeqlrlhrenaafydkeltgvpglellqrspdregsfy
vydvkvddrpafhrkmeaagimaglvsrrndehscvahlrtslpgldsvydrmvslpvgw
wlteqdrehvvatirsgw

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4xauC (C:)
mgsshhhhhhssglvprgshmiplfkvavsptaldrvaevfasgylgqgprvaefesala
arlgnprvvsvhsgtsglclalrlldapeerdevlstpltfeatnwailadgrritwvdv
dpatltmdlddlerkispatraiivvhwtgypvdldrlagildraerehgfrpaviedca
hawgasyrgvplgshgnmcvfsfqalkhltcgdgglltlpgdelheramlrrfygidrta
drlrgaydvaewglkwhmtdlnaaiglanletvdeqlrlhrenaafydkeltgvpglell
qrspdregsfyvydvkvddrpafhrkmeaagimaglvsrrndehscvahlrtslpgldsv
ydrmvslpvgwwlteqdrehvvatirsgw

    Sequence, based on observed residues (ATOM records): (download) 
    >4xauC (C:)
prgshmiplfkvavsptaldrvaevfasgylgqgprvaefesalaarlgnprvvsvhsgt
sglclalrlldapeerdevlstpltfeatnwailadgrritwvdvdpatltmdlddlerk
ispatraiivvhwtgypvdldrlagildraerehgfrpaviedcahawgasyrgvplgsh
gnmcvfsfqalkhltcgdgglltlpgdelheramlrrfygidrtadrlrgaydvaewglk
whmtdlnaaiglanletvdeqlrlhrenaafydkeltgvpglellqrspdregsfyvydv
kvddrpafhrkmeaagimaglvsrrndehscvahlrtslpgldsvydrmvslpvgwwlte
qdrehvvatirsgw

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4xauD (D:)
mgsshhhhhhssglvprgshmiplfkvavsptaldrvaevfasgylgqgprvaefesala
arlgnprvvsvhsgtsglclalrlldapeerdevlstpltfeatnwailadgrritwvdv
dpatltmdlddlerkispatraiivvhwtgypvdldrlagildraerehgfrpaviedca
hawgasyrgvplgshgnmcvfsfqalkhltcgdgglltlpgdelheramlrrfygidrta
drlrgaydvaewglkwhmtdlnaaiglanletvdeqlrlhrenaafydkeltgvpglell
qrspdregsfyvydvkvddrpafhrkmeaagimaglvsrrndehscvahlrtslpgldsv
ydrmvslpvgwwlteqdrehvvatirsgw

    Sequence, based on observed residues (ATOM records): (download) 
    >4xauD (D:)
sglvprgshmiplfkvavsptaldrvaevfasgylgqgprvaefesalaarlgnprvvsv
hsgtsglclalrlldapeerdevlstpltfeatnwailadgrritwvdvdpatltmdldd
lerkispatraiivvhwtgypvdldrlagildraerehgfrpaviedcahawgasyrgvp
lgshgnmcvfsfqalkhltcgdgglltlpgdelheramlrrfygidrtadrlrgaydvae
wglkwhmtdlnaaiglanletvdeqlrlhrenaafydkeltgvpglellqrspdregsfy
vydvkvddrpafhrkmeaagimaglvsrrndehscvahlrtslpgldsvydrmvslpvgw
wlteqdrehvvatirsgw

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4xauE (E:)
mgsshhhhhhssglvprgshmiplfkvavsptaldrvaevfasgylgqgprvaefesala
arlgnprvvsvhsgtsglclalrlldapeerdevlstpltfeatnwailadgrritwvdv
dpatltmdlddlerkispatraiivvhwtgypvdldrlagildraerehgfrpaviedca
hawgasyrgvplgshgnmcvfsfqalkhltcgdgglltlpgdelheramlrrfygidrta
drlrgaydvaewglkwhmtdlnaaiglanletvdeqlrlhrenaafydkeltgvpglell
qrspdregsfyvydvkvddrpafhrkmeaagimaglvsrrndehscvahlrtslpgldsv
ydrmvslpvgwwlteqdrehvvatirsgw

    Sequence, based on observed residues (ATOM records): (download) 
    >4xauE (E:)
rgshmiplfkvavsptaldrvaevfasgylgqgprvaefesalaarlgnprvvsvhsgts
glclalrlldapeerdevlstpltfeatnwailadgrritwvdvdpatltmdlddlerki
spatraiivvhwtgypvdldrlagildraerehgfrpaviedcahawgasyrgvplgshg
nmcvfsfqalkhltcgdgglltlpgdelheramlrrfygidrtadrlrgaydvaewglkw
hmtdlnaaiglanletvdeqlrlhrenaafydkeltgvpglellqrspdregsfyvydvk
vddrpafhrkmeaagimaglvsrrndehscvahlrtslpgldsvydrmvslpvgwwlteq
drehvvatirsgw

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4xauF (F:)
mgsshhhhhhssglvprgshmiplfkvavsptaldrvaevfasgylgqgprvaefesala
arlgnprvvsvhsgtsglclalrlldapeerdevlstpltfeatnwailadgrritwvdv
dpatltmdlddlerkispatraiivvhwtgypvdldrlagildraerehgfrpaviedca
hawgasyrgvplgshgnmcvfsfqalkhltcgdgglltlpgdelheramlrrfygidrta
drlrgaydvaewglkwhmtdlnaaiglanletvdeqlrlhrenaafydkeltgvpglell
qrspdregsfyvydvkvddrpafhrkmeaagimaglvsrrndehscvahlrtslpgldsv
ydrmvslpvgwwlteqdrehvvatirsgw

    Sequence, based on observed residues (ATOM records): (download) 
    >4xauF (F:)
rgshmiplfkvavsptaldrvaevfasgylgqgprvaefesalaarlgnprvvsvhsgts
glclalrlldapeerdevlstpltfeatnwailadgrritwvdvdpatltmdlddlerki
spatraiivvhwtgypvdldrlagildraerehgfrpaviedcahawgasyrgvplgshg
nmcvfsfqalkhltcgdgglltlpgdelheramlrrfygidrtadrlrgaydvaewglkw
hmtdlnaaiglanletvdeqlrlhrenaafydkeltgvpglellqrspdregsfyvydvk
vddrpafhrkmeaagimaglvsrrndehscvahlrtslpgldsvydrmvslpvgwwlteq
drehvvatirsgw

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >4xauG (G:)
mgsshhhhhhssglvprgshmiplfkvavsptaldrvaevfasgylgqgprvaefesala
arlgnprvvsvhsgtsglclalrlldapeerdevlstpltfeatnwailadgrritwvdv
dpatltmdlddlerkispatraiivvhwtgypvdldrlagildraerehgfrpaviedca
hawgasyrgvplgshgnmcvfsfqalkhltcgdgglltlpgdelheramlrrfygidrta
drlrgaydvaewglkwhmtdlnaaiglanletvdeqlrlhrenaafydkeltgvpglell
qrspdregsfyvydvkvddrpafhrkmeaagimaglvsrrndehscvahlrtslpgldsv
ydrmvslpvgwwlteqdrehvvatirsgw

    Sequence, based on observed residues (ATOM records): (download) 
    >4xauG (G:)
rgshmiplfkvavsptaldrvaevfasgylgqgprvaefesalaarlgnprvvsvhsgts
glclalrlldapeerdevlstpltfeatnwailadgrritwvdvdpatltmdlddlerki
spatraiivvhwtgypvdldrlagildraerehgfrpaviedcahawgasyrgvplgshg
nmcvfsfqalkhltcgdgglltlpgdelheramlrrfygidrtadrlrgaydvaewglkw
hmtdlnaaiglanletvdeqlrlhrenaafydkeltgvpglellqrspdregsfyvydvk
vddrpafhrkmeaagimaglvsrrndehscvahlrtslpgldsvydrmvslpvgwwlteq
drehvvatirsgw