PDB entry 4rfe

View 4rfe on RCSB PDB site
Description: Crystal structure of ADCC-potent ANTI-HIV-1 Rhesus macaque antibody JR4 Fab
Class: immune system
Keywords: hiv-1 gp120 specific antibody, cd4i antibody, adcc, hiv-1 env, anti-hiv-1 env antibody jr4, immune system
Deposited on 2014-09-25, released 2015-07-15
The last revision prior to the SCOPe 2.05 freeze date was dated 2015-07-15, with a file datestamp of 2015-07-10.
Experiment type: XRAY
Resolution: 1.91 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fab heavy chain of ADCC-potent anti-HIV-1 antibody JR4
    Species: Macaca mulatta [TaxId:9544]
    Gene: Fab heavy chain of ADCC-potent anti-HIV-1 antibody JR4
    Database cross-references and differences (RAF-indexed):
    • PDB 4RFE
  • Chain 'B':
    Compound: Fab light chain of ADCC-potent anti-HIV-1 antibody JR4
    Species: Macaca mulatta [TaxId:9544]
    Gene: Fab light chain of ADCC-potent anti-HIV-1 antibody JR4
    Database cross-references and differences (RAF-indexed):
    • PDB 4RFE
    Domains in SCOPe 2.05: d4rfeb1, d4rfeb2
  • Chain 'C':
    Compound: Fab heavy chain of ADCC-potent anti-HIV-1 antibody JR4
    Species: Macaca mulatta [TaxId:9544]
    Gene: Fab heavy chain of ADCC-potent anti-HIV-1 antibody JR4
    Database cross-references and differences (RAF-indexed):
    • PDB 4RFE
  • Chain 'D':
    Compound: Fab light chain of ADCC-potent anti-HIV-1 antibody JR4
    Species: Macaca mulatta [TaxId:9544]
    Gene: Fab light chain of ADCC-potent anti-HIV-1 antibody JR4
    Database cross-references and differences (RAF-indexed):
    • PDB 4RFE (0-End)
    Domains in SCOPe 2.05: d4rfed1, d4rfed2
  • Chain 'E':
    Compound: Fab heavy chain of ADCC-potent anti-HIV-1 antibody JR4
    Species: Macaca mulatta [TaxId:9544]
    Gene: Fab heavy chain of ADCC-potent anti-HIV-1 antibody JR4
    Database cross-references and differences (RAF-indexed):
    • PDB 4RFE
  • Chain 'F':
    Compound: Fab light chain of ADCC-potent anti-HIV-1 antibody JR4
    Species: Macaca mulatta [TaxId:9544]
    Gene: Fab light chain of ADCC-potent anti-HIV-1 antibody JR4
    Database cross-references and differences (RAF-indexed):
    • PDB 4RFE (0-End)
    Domains in SCOPe 2.05: d4rfef1, d4rfef2
  • Chain 'H':
    Compound: Fab heavy chain of ADCC-potent anti-HIV-1 antibody JR4
    Species: Macaca mulatta [TaxId:9544]
    Gene: Fab heavy chain of ADCC-potent anti-HIV-1 antibody JR4
    Database cross-references and differences (RAF-indexed):
    • PDB 4RFE
  • Chain 'L':
    Compound: Fab light chain of ADCC-potent anti-HIV-1 antibody JR4
    Species: Macaca mulatta [TaxId:9544]
    Gene: Fab light chain of ADCC-potent anti-HIV-1 antibody JR4
    Database cross-references and differences (RAF-indexed):
    • PDB 4RFE
    Domains in SCOPe 2.05: d4rfel1, d4rfel2
  • Heterogens: SO4, CL, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4rfeB (B:)
qsvltqppsvsaapgqkvtiscsgsssnigrsyvswyqqvpgaapklliydtnkrpsgvs
drfsgsksgssaslaitglqtgdeadyycgawdgslnvhifgsgtkltvlgqpkasplvt
lfppsseelqankatlvclisdfypgvvkvawkadgnsvntgvetttpskqsnnkyaass
ylsltsdqwkshksyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >4rfeB (B:)
vltqppsvsaapgqkvtiscsgsssnigrsyvswyqqvpgaapklliydtnkrpsgvsdr
fsgsksgssaslaitglqtgdeadyycgawdgslnvhifgsgtkltvlgqpkasplvtlf
ppsseelqankatlvclisdfypgvvkvawkadgnsvntgvetttpskqsnnkyaassyl
sltsdqwkshksyscqvthegstvektvap

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4rfeD (D:)
qsvltqppsvsaapgqkvtiscsgsssnigrsyvswyqqvpgaapklliydtnkrpsgvs
drfsgsksgssaslaitglqtgdeadyycgawdgslnvhifgsgtkltvlgqpkasplvt
lfppsseelqankatlvclisdfypgvvkvawkadgnsvntgvetttpskqsnnkyaass
ylsltsdqwkshksyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >4rfeD (D:)
qsvltqppsvsaapgqkvtiscsgsssnigrsyvswyqqvpgaapklliydtnkrpsgvs
drfsgsksgssaslaitglqtgdeadyycgawdgslnvhifgsgtkltvlgqpkasplvt
lfppsseelqankatlvclisdfypgvvkvawkadgnsvntgvetttpskqsnnkyaass
ylsltsdqwkshksyscqvthegstvektvap

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4rfeF (F:)
qsvltqppsvsaapgqkvtiscsgsssnigrsyvswyqqvpgaapklliydtnkrpsgvs
drfsgsksgssaslaitglqtgdeadyycgawdgslnvhifgsgtkltvlgqpkasplvt
lfppsseelqankatlvclisdfypgvvkvawkadgnsvntgvetttpskqsnnkyaass
ylsltsdqwkshksyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >4rfeF (F:)
qsvltqppsvsaapgqkvtiscsgsssnigrsyvswyqqvpgaapklliydtnkrpsgvs
drfsgsksgssaslaitglqtgdeadyycgawdgslnvhifgsgtkltvlgqpkasplvt
lfppsseelqankatlvclisdfypgvvkvawkadgnsvntgvetttpskqsnnkyaass
ylsltsdqwkshksyscqvthegstvektvap

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >4rfeL (L:)
qsvltqppsvsaapgqkvtiscsgsssnigrsyvswyqqvpgaapklliydtnkrpsgvs
drfsgsksgssaslaitglqtgdeadyycgawdgslnvhifgsgtkltvlgqpkasplvt
lfppsseelqankatlvclisdfypgvvkvawkadgnsvntgvetttpskqsnnkyaass
ylsltsdqwkshksyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >4rfeL (L:)
vltqppsvsaapgqkvtiscsgsssnigrsyvswyqqvpgaapklliydtnkrpsgvsdr
fsgsksgssaslaitglqtgdeadyycgawdgslnvhifgsgtkltvlgqpkasplvtlf
ppsseelqankatlvclisdfypgvvkvawkadgnsvntgvetttpskqsnnkyaassyl
sltsdqwkshksyscqvthegstvektvap