PDB entry 4qqq

View 4qqq on RCSB PDB site
Description: Crystal structure of pneumolysin from Streptococcus pneumoniae, in complex with mannose as a component of cell membrane
Class: toxin
Keywords: PLY, Cholesterol-dependent Cytolysin, Cholesterol/mannose binding, TOXIN
Deposited on 2014-06-27, released 2015-07-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pneumolysin
    Species: Streptococcus pneumoniae [TaxId:1313]
    Gene: ply
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2XU26 (13-End)
      • expression tag (0-12)
    Domains in SCOPe 2.08: d4qqqa2, d4qqqa3, d4qqqa4
  • Heterogens: MAN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4qqqA (A:)
hhhssglvprgshmankavndfilamnydkkkllthqgesienrfikegnqlpdefvvie
rkkrslstntsdisvtatndsrlypgallvvdetllennptllavdrapmtysidlpgla
ssdsflqvedpsnssvrgavndllakwhqdygqvnnvparmqyekitahsmeqlkvkfgs
dfektgnsldidfnsvhsgekqiqivnfkqiyytvsvdavknpgdvfqdtvtvedlkqrg
isaerplvyissvaygrqvylklettsksdeveaafealikgvkvapqtewkqildntev
kavilggdpssgarvvtgkvdmvedliqegsrftadhpglpisyttsflrdnvvatfqns
tdyvetkvtayrngdllldhsgayvaqyyitwnelsydhqgkevltpkawdrngqdltah
fttsiplkgnvrnlsvkirectglawewwrtvyektdlplvrkrtisiwgttlypqvedk
vend

    Sequence, based on observed residues (ATOM records): (download) 
    >4qqqA (A:)
hhhssglvprgshmankavndfilamnydkkkllthqgesienrfikegnqlpdefvvie
rkkrslstntsdisvtatndsrlypgallvvdetllennptllavdrapmtysidlpgla
ssdsflqvedpsnssvrgavndllakwhqdygqvnnvparmqyekitahsmeqlkvkfgs
dfektgnsldidfnsvhsgekqiqivnfkqiyytvsvdavknpgdvfqdtvtvedlkqrg
isaerplvyissvaygrqvylklettsksdeveaafealikgvkvapqtewkqildntev
kavilggdpssgarvvtgkvdmvedliqegsrftadhpglpisyttsflrdnvvatfqns
tdyvetkvtayrngdllldhsgayvaqyyitwnelsydhqgkevltpkawdrngqdltah
fttsiplkgnvrnlsvkirectglawewwrtvyektdlplvrkrtisiwgttlypqvedk
ven