PDB entry 4qlg
View 4qlg on RCSB PDB site
Description: Crystal structure of I14V DHFR mutant complexed with folate and NADP+
Class: oxidoreductase
Keywords: dihydrofolate-reductase like fold/Alpha and beta proteins (a/b), oxidoreductase activity, NADP(H) binding, oxidoreductase
Deposited on
2014-06-12, released
2014-11-26
The last revision prior to the SCOPe 2.05 freeze date was dated
2014-11-26, with a file datestamp of
2014-11-21.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: 0.176
AEROSPACI score: 0.55
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: dihydrofolate reductase
Species: Escherichia coli [TaxId:1403831]
Gene: folA, BN896_0046
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d4qlga_ - Chain 'B':
Compound: dihydrofolate reductase
Species: Escherichia coli [TaxId:1403831]
Gene: folA, BN896_0046
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d4qlgb_ - Heterogens: FOL, NAP, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>4qlgA (A:)
misliaalavdrvvgmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
gdthfpdyepddwesvfsefhdadaqnshsycfeilerr
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>4qlgB (B:)
misliaalavdrvvgmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
gdthfpdyepddwesvfsefhdadaqnshsycfeilerr