PDB entry 4qh6

View 4qh6 on RCSB PDB site
Description: Crystal structure of cruzain with nitrile inhibitor N-(2-AMINOETHYL)-NALPHA-BENZOYL-L-PHENYLALANINAMIDE
Class: Hydrolase/Hydrolase inhibitor
Keywords: Thiol protease, Hydrolase-Hydrolase inhibitor complex
Deposited on 2014-05-27, released 2015-08-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 3.13 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cruzipain
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: Cruzipain, GenBank M84342.1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4qh6a_
  • Chain 'B':
    Compound: Cruzipain
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: Cruzipain, GenBank M84342.1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4qh6b_
  • Chain 'C':
    Compound: Cruzipain
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: Cruzipain, GenBank M84342.1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4qh6c_
  • Chain 'D':
    Compound: Cruzipain
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: Cruzipain, GenBank M84342.1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4qh6d_
  • Chain 'E':
    Compound: Cruzipain
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: Cruzipain, GenBank M84342.1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4qh6e_
  • Heterogens: 33L

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4qh6A (A:)
apaavdwrargavtavkdqgqcgscwafsaignvecqwflaghpltnlseqmlvscdktd
sgcsgglmnnafewivqenngavytedsypyasgegisppcttsghtvgatitghvelpq
deaqiaawlavngpvavavdasswmtytggvmtscvseqldhgvllvgyndsaavpywii
knswttqwgeegyiriakgsnqclvkeeassavvg

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4qh6B (B:)
apaavdwrargavtavkdqgqcgscwafsaignvecqwflaghpltnlseqmlvscdktd
sgcsgglmnnafewivqenngavytedsypyasgegisppcttsghtvgatitghvelpq
deaqiaawlavngpvavavdasswmtytggvmtscvseqldhgvllvgyndsaavpywii
knswttqwgeegyiriakgsnqclvkeeassavvg

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4qh6C (C:)
apaavdwrargavtavkdqgqcgscwafsaignvecqwflaghpltnlseqmlvscdktd
sgcsgglmnnafewivqenngavytedsypyasgegisppcttsghtvgatitghvelpq
deaqiaawlavngpvavavdasswmtytggvmtscvseqldhgvllvgyndsaavpywii
knswttqwgeegyiriakgsnqclvkeeassavvg

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4qh6D (D:)
apaavdwrargavtavkdqgqcgscwafsaignvecqwflaghpltnlseqmlvscdktd
sgcsgglmnnafewivqenngavytedsypyasgegisppcttsghtvgatitghvelpq
deaqiaawlavngpvavavdasswmtytggvmtscvseqldhgvllvgyndsaavpywii
knswttqwgeegyiriakgsnqclvkeeassavvg

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4qh6E (E:)
apaavdwrargavtavkdqgqcgscwafsaignvecqwflaghpltnlseqmlvscdktd
sgcsgglmnnafewivqenngavytedsypyasgegisppcttsghtvgatitghvelpq
deaqiaawlavngpvavavdasswmtytggvmtscvseqldhgvllvgyndsaavpywii
knswttqwgeegyiriakgsnqclvkeeassavvg