PDB entry 4pbv

View 4pbv on RCSB PDB site
Description: Crystal structure of chicken receptor protein tyrosine phosphatase sigma in complex with TrkC
Class: signaling protein
Keywords: Signaling protein, Synapse Cell signalling Cell surface receptor
Deposited on 2014-04-14, released 2014-11-12
The last revision prior to the SCOPe 2.04 freeze date was dated 2014-11-19, with a file datestamp of 2014-11-14.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.211
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NT-3 growth factor receptor
    Species: Gallus gallus [TaxId:9031]
    Gene: NTRK3, TRKC
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q91044 (3-258)
      • expression tag (0-2)
      • engineered mutation (119)
      • engineered mutation (188)
      • engineered mutation (223)
      • engineered mutation (250)
      • expression tag (259-260)
  • Chain 'B':
    Compound: NT-3 growth factor receptor
    Species: Gallus gallus [TaxId:9031]
    Gene: NTRK3, TRKC
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q91044 (3-258)
      • expression tag (2)
      • engineered mutation (119)
      • engineered mutation (188)
      • engineered mutation (223)
      • engineered mutation (250)
      • expression tag (259)
  • Chain 'C':
    Compound: protein-tyrosine phosphatase crypalpha1 isoform
    Species: Gallus gallus [TaxId:9031]
    Gene: CRYPalpha1
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: protein-tyrosine phosphatase crypalpha1 isoform
    Species: Gallus gallus [TaxId:9031]
    Gene: CRYPalpha1
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: protein-tyrosine phosphatase crypalpha1 isoform
    Species: Gallus gallus [TaxId:9031]
    Gene: CRYPalpha1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4pbve1, d4pbve2
  • Heterogens: NAG, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4pbvE (E:)
etgesppvfikkpvdqigvsggvasfvcqatgdpkprvtwnkkgkkvnsqrfetiefdes
agavlriqplrtprdeniyecvaqnphgevtvhakltvlredqlppgfpnidmgpqlkvv
ertrtatmlcaasgnpdpeitwfkdflpvdpstsngrikqlrsgglqiesseetdqgkye
cvasnsagvrysspanlyvrvrrvaprfsilpvsheimpggnvnitcvavgspmpyvkwm
qgaedltpeddmpvgrnvleltdvkdsanytcvamsslgvieavaqitvkskghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4pbvE (E:)
esppvfikkpvdqigvsggvasfvcqatgdpkprvtwnksqrfetiefdesagavlriqp
lrtprdeniyecvaqnphgevtvhakltvlredqlppgfpnidmgpqlkvvertrtatml
caasgnpdpeitwfkdflpvdpstsngrikqlrsgglqiesseetdqgkyecvasnsagv
rysspanlyvrvrr