PDB entry 4p2x

View 4p2x on RCSB PDB site
Description: Swapped Dimer of Mycobacterial Adenylyl cyclase Rv1625c: Form 2
Class: lyase
Keywords: Adenylyl Cyclase, beta-alpha-beta sandwich, Domain swapping, Signal transduction
Deposited on 2014-03-05, released 2014-09-17
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-10-22, with a file datestamp of 2014-10-17.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.199
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: adenylate cyclase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: cya, Rv1625c, MT1661, MTCY01B2.17c
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4p2xa_
  • Chain 'B':
    Compound: adenylate cyclase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: cya, Rv1625c, MT1661, MTCY01B2.17c
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4p2xb_
  • Heterogens: SO4, PEG, MG, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4p2xA (A:)
msyyhhhhhhdydipttenlyfqgameaehdrseallanmlpasiaerlkeperniiadk
ydeasvlfadivgfterasstapadlvrfldrlysafdelvdqhglekikvsgdsymvvs
gvprprpdhtqaladfaldmtnvaaqlkdprgnpvplrvglatgpvvagvvgsrrffydv
wgdavnvasrmestdsvgqiqvpdevyerlkddfvlrerghinvkgkgvmrtwyligrkv
aadpgevrgaeprtagv

    Sequence, based on observed residues (ATOM records): (download) 
    >4p2xA (A:)
rniiadkydeasvlfadivpalvrfldrlysafdelvdqhglekikgdsymvvsgvprpr
pdhtqaladfaldmtnvaaqlkdprnpvplrvglatgpvvagvvgsrrffydvwgdavnv
asrmestdsvgqiqvpdevyerlkddfvlrerghinvmrtwyligrk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4p2xB (B:)
msyyhhhhhhdydipttenlyfqgameaehdrseallanmlpasiaerlkeperniiadk
ydeasvlfadivgfterasstapadlvrfldrlysafdelvdqhglekikvsgdsymvvs
gvprprpdhtqaladfaldmtnvaaqlkdprgnpvplrvglatgpvvagvvgsrrffydv
wgdavnvasrmestdsvgqiqvpdevyerlkddfvlrerghinvkgkgvmrtwyligrkv
aadpgevrgaeprtagv

    Sequence, based on observed residues (ATOM records): (download) 
    >4p2xB (B:)
erniiadkydeasvlfadivrfldrlysafdelvdqhglekikvsgdsymvvsgvprprp
dhtqaladfaldmtnvaaqlkdrgnpvplrvglatgpvvagvvgsrrffydvwgdavnva
srmestvgqiqvpdevyerlkddfvlrerghinvkgkgvmrtwyligrkvaa