PDB entry 4mll

View 4mll on RCSB PDB site
Description: The 1.4 A structure of the class D beta-lactamase OXA-1 K70D complexed with oxacillin
Class: hydrolase/antibiotic
Keywords: Hydrolase,Oxacillinase, Antibiotic Resistance, HYDROLASE-ANTIBIOTIC complex
Deposited on 2013-09-06, released 2013-10-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-01-08, with a file datestamp of 2014-01-03.
Experiment type: XRAY
Resolution: 1.37 Å
R-factor: 0.165
AEROSPACI score: 0.63 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: beta-lactamase OXA-1
    Species: Escherichia coli [TaxId:562]
    Gene: bla, bla oxa1, oxa1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13661 (Start-250)
      • engineered mutation (48)
    Domains in SCOPe 2.08: d4mlla_
  • Chain 'B':
    Compound: beta-lactamase OXA-1
    Species: Escherichia coli [TaxId:562]
    Gene: bla, bla oxa1, oxa1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13661 (0-250)
      • engineered mutation (48)
    Domains in SCOPe 2.08: d4mllb_
  • Chain 'C':
    Compound: beta-lactamase OXA-1
    Species: Escherichia coli [TaxId:562]
    Gene: bla, bla oxa1, oxa1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13661 (0-250)
      • engineered mutation (48)
    Domains in SCOPe 2.08: d4mllc_
  • Chain 'D':
    Compound: beta-lactamase OXA-1
    Species: Escherichia coli [TaxId:562]
    Gene: bla, bla oxa1, oxa1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13661 (Start-250)
      • engineered mutation (48)
    Domains in SCOPe 2.08: d4mlld_
  • Heterogens: 1S6, PO4, MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4mllA (A:)
stdistvasplfegtegcfllydastnaeiaqfnkakcatqmapdstfdialslmafdae
iidqktifkwdktpkgmeiwnsnhtpktwmqfsvvwvsqeitqkiglnkiknylkdfdyg
nqdfsgdkernnglteawlesslkispeeqiqflrkiinhnlpvknsaientienmylqd
ldnstklygktgagftanrtlqngwfegfiisksghkyvfvsaltgnlgsnltssikakk
naitilntlnl

    Sequence, based on observed residues (ATOM records): (download) 
    >4mllA (A:)
tdistvasplfegtegcfllydastnaeiaqfnkakcatqmapdstfdialslmafdaei
idqktifkwdktpkgmeiwnsnhtpktwmqfsvvwvsqeitqkiglnkiknylkdfdygn
qdfsgdkernnglteawlesslkispeeqiqflrkiinhnlpvknsaientienmylqdl
dnstklygktgagftanrtlqngwfegfiisksghkyvfvsaltgnlgsnltssikakkn
aitilntlnl

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4mllB (B:)
stdistvasplfegtegcfllydastnaeiaqfnkakcatqmapdstfdialslmafdae
iidqktifkwdktpkgmeiwnsnhtpktwmqfsvvwvsqeitqkiglnkiknylkdfdyg
nqdfsgdkernnglteawlesslkispeeqiqflrkiinhnlpvknsaientienmylqd
ldnstklygktgagftanrtlqngwfegfiisksghkyvfvsaltgnlgsnltssikakk
naitilntlnl

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4mllC (C:)
stdistvasplfegtegcfllydastnaeiaqfnkakcatqmapdstfdialslmafdae
iidqktifkwdktpkgmeiwnsnhtpktwmqfsvvwvsqeitqkiglnkiknylkdfdyg
nqdfsgdkernnglteawlesslkispeeqiqflrkiinhnlpvknsaientienmylqd
ldnstklygktgagftanrtlqngwfegfiisksghkyvfvsaltgnlgsnltssikakk
naitilntlnl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4mllD (D:)
stdistvasplfegtegcfllydastnaeiaqfnkakcatqmapdstfdialslmafdae
iidqktifkwdktpkgmeiwnsnhtpktwmqfsvvwvsqeitqkiglnkiknylkdfdyg
nqdfsgdkernnglteawlesslkispeeqiqflrkiinhnlpvknsaientienmylqd
ldnstklygktgagftanrtlqngwfegfiisksghkyvfvsaltgnlgsnltssikakk
naitilntlnl

    Sequence, based on observed residues (ATOM records): (download) 
    >4mllD (D:)
tdistvasplfegtegcfllydastnaeiaqfnkakcatqmapdstfdialslmafdaei
idqktifkwdktpkgmeiwnsnhtpktwmqfsvvwvsqeitqkiglnkiknylkdfdygn
qdfsgdkernnglteawlesslkispeeqiqflrkiinhnlpvknsaientienmylqdl
dnstklygktgagftanrtlqngwfegfiisksghkyvfvsaltgnlgsnltssikakkn
aitilntlnl