PDB entry 4mkt

View 4mkt on RCSB PDB site
Description: Human Leukotriene A4 Hydrolase in complex with Pro-Gly-Pro analogue and 4-(4-benzylphenyl)thiazol-2-amine
Class: hydrolase
Keywords: Leukotriene A4 Hydrolase, Metalloprotein, Hydrolase, protease, Zinc binding
Deposited on 2013-09-05, released 2014-03-12
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-04-23, with a file datestamp of 2014-04-18.
Experiment type: XRAY
Resolution: 1.62 Å
R-factor: 0.158
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Leukotriene A-4 hydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: LTA4, LTA4H
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4mkta1, d4mkta2, d4mkta3
  • Heterogens: ZN, 28T, 1V6, YB, ACY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4mktA (A:)
mpeivdtcslaspasvcrtkhlhlrcsvdftrrtltgtaaltvqsqednlrslvldtkdl
tiekvvingqevkyalgerqsykgspmeislpialsknqeivieisfetspkssalqwlt
peqtsgkehpylfsqcqaihcrailpcqdtpsvkltytaevsvpkelvalmsairdgetp
dpedpsrkiykfiqkvpipcylialvvgalesrqigprtlvwsekeqveksayefsetes
mlkiaedlggpyvwgqydllvlppsfpyggmenpcltfvtptllagdkslsnviaheish
swtgnlvtnktwdhfwlneghtvylerhicgrlfgekfrhfnalggwgelqnsvktfget
hpftklvvdltdidpdvayssvpyekgfallfyleqllggpeiflgflkayvekfsyksi
ttddwkdflysyfkdkvdvlnqvdwnawlyspglppikpnydmtltnacialsqrwitak
eddlnsfnatdlkdlsshqlneflaqtlqraplplghikrmqevynfnainnseirfrwl
rlciqskwedaiplalkmateqgrmkftrplfkdlaafdkshdqavrtyqehkasmhpvt
amlvgkdlkvd

    Sequence, based on observed residues (ATOM records): (download) 
    >4mktA (A:)
ivdtcslaspasvcrtkhlhlrcsvdftrrtltgtaaltvqsqednlrslvldtkdltie
kvvingqevkyalgerqsykgspmeislpialsknqeivieisfetspkssalqwltpeq
tsgkehpylfsqcqaihcrailpcqdtpsvkltytaevsvpkelvalmsairdgetpdpe
dpsrkiykfiqkvpipcylialvvgalesrqigprtlvwsekeqveksayefsetesmlk
iaedlggpyvwgqydllvlppsfpyggmenpcltfvtptllagdkslsnviaheishswt
gnlvtnktwdhfwlneghtvylerhicgrlfgekfrhfnalggwgelqnsvktfgethpf
tklvvdltdidpdvayssvpyekgfallfyleqllggpeiflgflkayvekfsyksittd
dwkdflysyfkdkvdvlnqvdwnawlyspglppikpnydmtltnacialsqrwitakedd
lnsfnatdlkdlsshqlneflaqtlqraplplghikrmqevynfnainnseirfrwlrlc
iqskwedaiplalkmateqgrmkftrplfkdlaafdkshdqavrtyqehkasmhpvtaml
vgkdlkvd