PDB entry 4m19

View 4m19 on RCSB PDB site
Description: dihydrodipicolinate synthase from C. jejuni with pyruvate bound to the active site and Lysine bound to allosteric site
Class: lyase
Keywords: schiff-base, aldolase, TIM barrel, LYASE
Deposited on 2013-08-02, released 2015-01-14
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-01-14, with a file datestamp of 2015-01-09.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.167
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 4-hydroxy-tetrahydrodipicolinate synthase
    Species: Campylobacter jejuni subsp. jejuni [TaxId:192222]
    Gene: Cj0806, dapA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4m19a_
  • Chain 'B':
    Compound: 4-hydroxy-tetrahydrodipicolinate synthase
    Species: Campylobacter jejuni subsp. jejuni [TaxId:192222]
    Gene: Cj0806, dapA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4m19b_
  • Chain 'C':
    Compound: 4-hydroxy-tetrahydrodipicolinate synthase
    Species: Campylobacter jejuni subsp. jejuni [TaxId:192222]
    Gene: Cj0806, dapA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4m19c_
  • Chain 'D':
    Compound: 4-hydroxy-tetrahydrodipicolinate synthase
    Species: Campylobacter jejuni subsp. jejuni [TaxId:192222]
    Gene: Cj0806, dapA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4m19d_
  • Heterogens: LYS, EDO, PG4, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4m19A (A:)
hhhhhhasmdkniiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesa
tltheehrtcieiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyyn
kptqqglyehykaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgni
dkcvdllaheprmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenyke
akkindelyninkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkk
ykikgf

    Sequence, based on observed residues (ATOM records): (download) 
    >4m19A (A:)
kniiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesatltheehrtc
ieiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyynkptqqglyeh
ykaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgnidkcvdllahe
prmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenykeakkindelyn
inkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkkykikgf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4m19B (B:)
hhhhhhasmdkniiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesa
tltheehrtcieiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyyn
kptqqglyehykaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgni
dkcvdllaheprmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenyke
akkindelyninkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkk
ykikgf

    Sequence, based on observed residues (ATOM records): (download) 
    >4m19B (B:)
niiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesatltheehrtci
eiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyynkptqqglyehy
kaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgnidkcvdllahep
rmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenykeakkindelyni
nkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkkykikgf

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4m19C (C:)
hhhhhhasmdkniiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesa
tltheehrtcieiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyyn
kptqqglyehykaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgni
dkcvdllaheprmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenyke
akkindelyninkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkk
ykikgf

    Sequence, based on observed residues (ATOM records): (download) 
    >4m19C (C:)
niiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesatltheehrtci
eiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyynkptqqglyehy
kaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgnidkcvdllahep
rmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenykeakkindelyni
nkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkkykikgf

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4m19D (D:)
hhhhhhasmdkniiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesa
tltheehrtcieiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyyn
kptqqglyehykaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgni
dkcvdllaheprmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenyke
akkindelyninkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkk
ykikgf

    Sequence, based on observed residues (ATOM records): (download) 
    >4m19D (D:)
niiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesatltheehrtci
eiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyynkptqqglyehy
kaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgnidkcvdllahep
rmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenykeakkindelyni
nkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkkykikgf