PDB entry 4ly8

View 4ly8 on RCSB PDB site
Description: dihydrodipicolinate synthase from C. jejuni with pyruvate bound to the active site
Class: lyase
Keywords: schiff-base, aldolase, TIM barrel, type 1 aldolase catalysing condensation of pyruvate and S-aspartate-B-semi-aldehyde, LYASE
Deposited on 2013-07-30, released 2015-01-14
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-01-14, with a file datestamp of 2015-01-09.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.211
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 4-hydroxy-tetrahydrodipicolinate synthase
    Species: Campylobacter jejuni subsp. jejuni [TaxId:192222]
    Gene: Cj0806, dapA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4ly8a_
  • Chain 'B':
    Compound: 4-hydroxy-tetrahydrodipicolinate synthase
    Species: Campylobacter jejuni subsp. jejuni [TaxId:192222]
    Gene: Cj0806, dapA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4ly8b_
  • Chain 'C':
    Compound: 4-hydroxy-tetrahydrodipicolinate synthase
    Species: Campylobacter jejuni subsp. jejuni [TaxId:192222]
    Gene: Cj0806, dapA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4ly8c_
  • Chain 'D':
    Compound: 4-hydroxy-tetrahydrodipicolinate synthase
    Species: Campylobacter jejuni subsp. jejuni [TaxId:192222]
    Gene: Cj0806, dapA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4ly8d_
  • Heterogens: EDO, PGE, ACT, GOL, PG4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ly8A (A:)
hhhhhhgsmdkniiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesa
tltheehrtcieiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyyn
kptqqglyehykaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgni
dkcvdllaheprmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenyke
akkindelyninkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkk
ykikgf

    Sequence, based on observed residues (ATOM records): (download) 
    >4ly8A (A:)
mdkniiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesatltheehr
tcieiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyynkptqqgly
ehykaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgnidkcvdlla
heprmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenykeakkindel
yninkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkkykikgf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4ly8B (B:)
hhhhhhgsmdkniiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesa
tltheehrtcieiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyyn
kptqqglyehykaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgni
dkcvdllaheprmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenyke
akkindelyninkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkk
ykikgf

    Sequence, based on observed residues (ATOM records): (download) 
    >4ly8B (B:)
dkniiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesatltheehrt
cieiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyynkptqqglye
hykaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgnidkcvdllah
eprmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenykeakkindely
ninkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkkykikgf

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4ly8C (C:)
hhhhhhgsmdkniiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesa
tltheehrtcieiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyyn
kptqqglyehykaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgni
dkcvdllaheprmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenyke
akkindelyninkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkk
ykikgf

    Sequence, based on observed residues (ATOM records): (download) 
    >4ly8C (C:)
mdkniiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesatltheehr
tcieiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyynkptqqgly
ehykaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgnidkcvdlla
heprmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenykeakkindel
yninkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkkykikgf

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4ly8D (D:)
hhhhhhgsmdkniiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesa
tltheehrtcieiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyyn
kptqqglyehykaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgni
dkcvdllaheprmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenyke
akkindelyninkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkk
ykikgf

    Sequence, based on observed residues (ATOM records): (download) 
    >4ly8D (D:)
dkniiigamtalitpfkngkvdeqsyarlikrqiengidavvpvgttgesatltheehrt
cieiavetckgtkvkvlagagsnatheavglakfakehgadgilsvapyynkptqqglye
hykaiaqsvdipvllynvpgrtgceistdtiiklfrdceniygvxeasgnidkcvdllah
eprmmlisgedainypilsnggkgvisvtsnllpdmisalthfaldenykeakkindely
ninkilfcesnpipiktamylaglieslefrlplcspskenfakieevmkkykikgf