PDB entry 4k4s

View 4k4s on RCSB PDB site
Description: Poliovirus polymerase elongation complex (r3_form)
Class: Transferase/rna
Keywords: polymerase, RNA-dependent RNA polymerase, protein-RNA complex, Transferase-rna complex
Deposited on 2013-04-12, released 2013-05-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-07-03, with a file datestamp of 2013-06-28.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.2
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: RNA-directed RNA polymerase 3D-POL
    Species: Human poliovirus 1 [TaxId:12081]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03300 (0-460)
      • engineered mutation (445)
      • expression tag (461)
    Domains in SCOPe 2.08: d4k4sa1, d4k4sa2
  • Chain 'B':
    Compound: RNA (5'-r(*ap*ap*gp*up*cp*up*cp*cp*ap*gp*gp*up*cp*up*cp*up*cp*gp*cp*gp*ap*ap*a)-3')
  • Chain 'C':
    Compound: RNA (5'-r(*up*gp*up*up*cp*gp*cp*gp*ap*gp*ap*gp*a)-3')
  • Chain 'D':
    Compound: RNA (5'-r(*gp*gp*gp*ap*gp*ap*up*gp*a)-3')
  • Chain 'E':
    Compound: RNA-directed RNA polymerase 3D-POL
    Species: Human poliovirus 1 [TaxId:12081]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03300 (0-460)
      • engineered mutation (445)
      • expression tag (461)
    Domains in SCOPe 2.08: d4k4se1, d4k4se2
  • Chain 'F':
    Compound: RNA (5'-r(*ap*ap*gp*up*cp*up*cp*cp*ap*gp*gp*up*cp*up*cp*up*cp*gp*cp*gp*ap*ap*a)-3')
  • Chain 'G':
    Compound: RNA (5'-r(*up*gp*up*up*cp*gp*cp*gp*ap*gp*ap*gp*a)-3')
  • Chain 'H':
    Compound: RNA (5'-r(*gp*gp*gp*ap*gp*ap*up*gp*a)-3')
  • Heterogens: ZN, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4k4sA (A:)
geiqwmrpskevgypiinapsktklepsafhyvfegvkepavltkndprlktdfeeaifs
kyvgnkitevdeymkeavdhyagqlmsldinteqmcledamygtdglealdlstsagypy
vamgkkkrdilnkqtrdtkemqklldtyginlplvtyvkdelrsktkveqgksrlieass
lndsvamrmafgnlyaafhknpgvitgsavgcdpdlfwskipvlmeeklfafdytgydas
lspawfealkmvlekigfgdrvdyidylnhshhlyknktycvkggmpsgcsgtsifnsmi
nnliirtlllktykgidldhlkmiaygddviasyphevdasllaqsgkdygltmtpadks
atfetvtwenvtflkrffradekypflihpvmpmkeihesirwtkdprntqdhvrslcll
awhngeeeynkflakirsvpigraldlpeystlyrrwldsfgssshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4k4sA (A:)
geiqwmrpskevgypiinapsktklepsafhyvfegvkepavltkndprlktdfeeaifs
kyvgnkitevdeymkeavdhyagqlmsldinteqmcledamygtdglealdlstsagypy
vamgkkkrdilnkqtrdtkemqklldtyginlplvtyvkdelrsktkveqgksrlieass
lndsvamrmafgnlyaafhknpgvitgsavgcdpdlfwskipvlmeeklfafdytgydas
lspawfealkmvlekigfgdrvdyidylnhshhlyknktycvkggmpsgcsgtsifnsmi
nnliirtlllktykgidldhlkmiaygddviasyphevdasllaqsgkdygltmtpadks
atfetvtwenvtflkrffradekypflihpvmpmkeihesirwtkdprntqdhvrslcll
awhngeeeynkflakirsvpigraldlpeystlyrrwldsfg

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4k4sE (E:)
geiqwmrpskevgypiinapsktklepsafhyvfegvkepavltkndprlktdfeeaifs
kyvgnkitevdeymkeavdhyagqlmsldinteqmcledamygtdglealdlstsagypy
vamgkkkrdilnkqtrdtkemqklldtyginlplvtyvkdelrsktkveqgksrlieass
lndsvamrmafgnlyaafhknpgvitgsavgcdpdlfwskipvlmeeklfafdytgydas
lspawfealkmvlekigfgdrvdyidylnhshhlyknktycvkggmpsgcsgtsifnsmi
nnliirtlllktykgidldhlkmiaygddviasyphevdasllaqsgkdygltmtpadks
atfetvtwenvtflkrffradekypflihpvmpmkeihesirwtkdprntqdhvrslcll
awhngeeeynkflakirsvpigraldlpeystlyrrwldsfgssshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4k4sE (E:)
geiqwmrpskevgypiinapsktklepsafhyvfegvkepavltkndprlktdfeeaifs
kyvgnkitevdeymkeavdhyagqlmsldinteqmcledamygtdglealdlstsagypy
vamgkkkrdilnkqtrdtkemqklldtyginlplvtyvkdelrsktkveqgksrlieass
lndsvamrmafgnlyaafhknpgvitgsavgcdpdlfwskipvlmeeklfafdytgydas
lspawfealkmvlekigfgdrvdyidylnhshhlyknktycvkggmpsgcsgtsifnsmi
nnliirtlllktykgidldhlkmiaygddviasyphevdasllaqsgkdygltmtpadks
atfetvtwenvtflkrffradekypflihpvmpmkeihesirwtkdprntqdhvrslcll
awhngeeeynkflakirsvpigraldlpeystlyrrwldsfg

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.