PDB entry 4j2j

View 4j2j on RCSB PDB site
Description: Crystal structure of AXH domain complex with Capicua
Class: transcription regulator
Keywords: AXH domain, protein-protein interaction, Capicua, TRANSCRIPTION REGULATOR
Deposited on 2013-02-04, released 2013-04-03
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-04-03, with a file datestamp of 2013-03-29.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.223
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ataxin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: ATXN1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54253 (Start-128)
      • engineered mutation (19)
      • engineered mutation (44)
    Domains in SCOPe 2.06: d4j2ja_
  • Chain 'B':
    Compound: ataxin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: ATXN1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54253 (Start-128)
      • engineered mutation (19)
      • engineered mutation (44)
    Domains in SCOPe 2.06: d4j2jb_
  • Chain 'C':
    Compound: ataxin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: ATXN1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54253
      • engineered mutation (19)
      • engineered mutation (44)
    Domains in SCOPe 2.06: d4j2jc_
  • Chain 'D':
    Compound: Protein capicua homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: CIC
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Protein capicua homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: CIC
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Protein capicua homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: CIC
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4j2jA (A:)
efspaaapptlppyfmkgsmiqlangelkkvedlktedfiqsaemsndlkidsstverie
dshspgvaviqfavgehraqvsvevlveypffvfgqgwssccpertsqlfdlpcsklsvg
dvcisltlk

    Sequence, based on observed residues (ATOM records): (download) 
    >4j2jA (A:)
ptlppyfmkgsmiqlangelkkvedlktedfiqsaemsndlkidsstveriedshspgva
viqfavgehraqvsvevlveypffvfgqgwssccpertsqlfdlpcsklsvgdvcisltl
k

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4j2jB (B:)
efspaaapptlppyfmkgsmiqlangelkkvedlktedfiqsaemsndlkidsstverie
dshspgvaviqfavgehraqvsvevlveypffvfgqgwssccpertsqlfdlpcsklsvg
dvcisltlk

    Sequence, based on observed residues (ATOM records): (download) 
    >4j2jB (B:)
ptlppyfmkgsmiqlangelkkvedlktedfiqsaemsndlkidsstveriedshvaviq
favgehraqvsvevlveypffvfgqgwssccpertsqlfdlpcsklsvgdvcisltlk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4j2jC (C:)
efspaaapptlppyfmkgsmiqlangelkkvedlktedfiqsaemsndlkidsstverie
dshspgvaviqfavgehraqvsvevlveypffvfgqgwssccpertsqlfdlpcsklsvg
dvcisltlk

    Sequence, based on observed residues (ATOM records): (download) 
    >4j2jC (C:)
lppyfmkgsmiqlangelkkvedlktedfiqsaemsnlkidsstveriedshspgvaviq
favgehraqvsvevlveypffvfgqgwssccpertsqlfdlpcsklsvgdvcisl

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.