PDB entry 4iuo

View 4iuo on RCSB PDB site
Description: 1.8 Angstrom Crystal Structure of the Salmonella enterica 3-Dehydroquinate Dehydratase (aroD) K170M Mutant in Complex with Quinate
Class: lyase
Keywords: structural genomics, NIAID, National Institute of Allergy and Infectious Diseases, Center for Structural Genomics of Infectious Diseases, CSGID, TIM barrel, LYASE
Deposited on 2013-01-21, released 2013-01-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-dehydroquinate dehydratase
    Species: Salmonella enterica subsp. enterica serovar Typhimurium [TaxId:99287]
    Gene: aroD, STM1358
    Database cross-references and differences (RAF-indexed):
    • Uniprot P58687 (24-End)
      • expression tag (16-23)
      • engineered mutation (193)
    Domains in SCOPe 2.07: d4iuoa1, d4iuoa2
  • Chain 'B':
    Compound: 3-dehydroquinate dehydratase
    Species: Salmonella enterica subsp. enterica serovar Typhimurium [TaxId:99287]
    Gene: aroD, STM1358
    Database cross-references and differences (RAF-indexed):
    • Uniprot P58687 (24-275)
      • expression tag (16-23)
      • engineered mutation (193)
    Domains in SCOPe 2.07: d4iuob1, d4iuob2
  • Heterogens: QIC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4iuoA (A:)
mhhhhhhssgvdlgtenlyfqsnamktvtvrdlvvgegapkiivslmgktitdvkseala
yreadfdilewrvdhfanvttaesvleaagaireiitdkpllftfrsakeggeqalttgq
yidlnraavdsglvdmidlelftgddevkatvgyahqhnvavimsnhdfhktpaaeeivq
rlrkmqelgadipmiavmpqtkadvltlltatvemqeryadrpiitmsmsktgvisrlag
evfgsaatfgavkkasapgqisvadlrtvltilhqa

    Sequence, based on observed residues (ATOM records): (download) 
    >4iuoA (A:)
nlyfqsnamktvtvrdlvvgegapkiivslmgktitdvksealayreadfdilewrvdhf
anvttaesvleaagaireiitdkpllftfrsakeggeqalttgqyidlnraavdsglvdm
idlelftgddevkatvgyahqhnvavimsnhdfhktpaaeeivqrlrkmqelgadipmia
vmpqtkadvltlltatvemqeryadrpiitmsmsktgvisrlagevfgsaatfgavkkas
apgqisvadlrtvltilhq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4iuoB (B:)
mhhhhhhssgvdlgtenlyfqsnamktvtvrdlvvgegapkiivslmgktitdvkseala
yreadfdilewrvdhfanvttaesvleaagaireiitdkpllftfrsakeggeqalttgq
yidlnraavdsglvdmidlelftgddevkatvgyahqhnvavimsnhdfhktpaaeeivq
rlrkmqelgadipmiavmpqtkadvltlltatvemqeryadrpiitmsmsktgvisrlag
evfgsaatfgavkkasapgqisvadlrtvltilhqa

    Sequence, based on observed residues (ATOM records): (download) 
    >4iuoB (B:)
nlyfqsnamktvtvrdlvvgegapkiivslmgktitdvksealayreadfdilewrvdhf
anvttaesvleaagaireiitdkpllftfrsakeggeqalttgqyidlnraavdsglvdm
idlelftgddevkatvgyahqhnvavimsnhdfhktpaaeeivqrlrkmqelgadipmia
vmpqtkadvltlltatvemqeryadrpiitmsmsktgvisrlagevfgsaatfgavkkas
apgqisvadlrtvltilhqa