PDB entry 4hu7

View 4hu7 on RCSB PDB site
Description: E. coli thioredoxin variant with Pro76 as single proline residue
Class: oxidoreductase
Keywords: cisproline, Thioredoxin fold, protein disulfide oxidoreductase activity, oxidoreductase
Deposited on 2012-11-02, released 2013-05-29
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-07-03, with a file datestamp of 2013-06-28.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: 0.163
AEROSPACI score: 0.7 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thioredoxin-1
    Species: Escherichia coli [TaxId:83333]
    Gene: trxA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0AA25 (0-End)
      • engineered mutation (33)
      • engineered mutation (39)
      • engineered mutation (63)
      • engineered mutation (67)
    Domains in SCOPe 2.05: d4hu7a_
  • Chain 'B':
    Compound: Thioredoxin-1
    Species: Escherichia coli [TaxId:83333]
    Gene: trxA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0AA25
      • engineered mutation (33)
      • engineered mutation (39)
      • engineered mutation (63)
      • engineered mutation (67)
    Domains in SCOPe 2.05: d4hu7b_
  • Heterogens: CU, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4hu7A (A:)
sdkiihltddsfdtdvlkadgailvdfwaewcgackmiaaildeiadeyqgkltvaklni
dqnagtaakygirgiptlllfkngevaatkvgalskgqlkefldanla

    Sequence, based on observed residues (ATOM records): (download) 
    >4hu7A (A:)
sdkiihltddsfdtdvlkadgailvdfwaewcgackmiaaildeiadeyqgkltvaklni
dqnagtaakygirgiptlllfkngevaatkvgalskgqlkefldanl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4hu7B (B:)
sdkiihltddsfdtdvlkadgailvdfwaewcgackmiaaildeiadeyqgkltvaklni
dqnagtaakygirgiptlllfkngevaatkvgalskgqlkefldanla

    Sequence, based on observed residues (ATOM records): (download) 
    >4hu7B (B:)
iihltddsfdtdvlkadgailvdfwaewcgackmiaaildeiadeyqgkltvaklnidqn
agtaakygirgiptlllfkngevaatkvgalskgqlkefldanl