PDB entry 4frh

View 4frh on RCSB PDB site
Description: Crystal Structure of BBBB+UDP+Gal at pH 7.5 with MPD as the cryoprotectant
Class: transferase
Keywords: manganese, abo rossmann fold, retaining glycosyltransferase, glycoprotein, blood group antigen, metal-binding, transferase
Deposited on 2012-06-26, released 2013-12-25
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-02-26, with a file datestamp of 2014-02-21.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.174
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histo-blood group ABO system transferase
    Species: Homo sapiens [TaxId:9606]
    Gene: ABO
    Database cross-references and differences (RAF-indexed):
    • Uniprot H6A2X0
      • see remark 999 (132)
    Domains in SCOPe 2.05: d4frha_
  • Heterogens: UDP, GAL, PEG, MN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4frhA (A:)
mvslprmvypqpkvltpcrkdvlvvtpwlapivwegtfnidilneqfrlqnttigltvfa
ikkyvaflklfletaekhfmvghrvhyyvftdqpaavprvtlgtgrqlsvlevgaykrwq
dvsmrrmemisdgcerrflsevdylvcvdvdmefrdhvgveiltplfgtlhpsfygssre
aftyerrpqsqayipkdegdfyymgaffggsvqevqrltrachqammvdqangieavwhd
eshlnkyllrhkptkvlspeylwdqqllgwpavlrklrftavpknhqavrnpe

    Sequence, based on observed residues (ATOM records): (download) 
    >4frhA (A:)
vypqpkvltpcrkdvlvvtpwlapivwegtfnidilneqfrlqnttigltvfaikkyvaf
lklfletaekhfmvghrvhyyvftdqpaavprvtlgtgrqlsvlevgqdvsmrrmemisg
cerrflsevdylvcvdvdmefrdhvgveiltplfgtlhpsfygssreaftyerrpqsqay
ipkdegdfyymgaffggsvqevqrltrachqammvdqangieavwhdeshlnkyllrhkp
tkvlspeylwdqqllgwpavlrklrftavpk