PDB entry 4fkt
View 4fkt on RCSB PDB site
Description: Crystal structure of the cdk2 in complex with oxindole inhibitor
Class: transferase/transferase inhibitor
Keywords: alpha and beta protein (a+b), transferase-transferase inhibitor complex
Deposited on
2012-06-13, released
2013-05-08
The last revision prior to the SCOPe 2.08 freeze date was dated
2013-05-22, with a file datestamp of
2013-05-17.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.169
AEROSPACI score: 0.61
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: cyclin-dependent kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: CDK2, CDKN2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4fkta_ - Heterogens: 48K, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4fktA (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
Sequence, based on observed residues (ATOM records): (download)
>4fktA (A:)
menfqkvekigegtygvvykarnkltgevvalkkipstaireisllkelnhpnivklldv
ihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlk
pqnllintegaikladfglarafevvtlwyrapeillgckyystavdiwslgcifaemvt
rralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvpplded
grsllsqmlhydpnkrisakaalahpffqdvtkpvphl