PDB entry 4eem

View 4eem on RCSB PDB site
Description: Crystal structure of human M340H-beta-1,4-galactosyltransferase-1 (M340H-B4GAL-T1) in complex with GLCNAC-BETA1,6-MAN-ALPHA-methyl
Class: Transferase
Keywords: Protein carbohydrate interactions, GT-A fold, Glycosyltransferase, UDP-Galactose, Transferase
Deposited on 2012-03-28, released 2012-07-04
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-03-26, with a file datestamp of 2014-03-21.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.194
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-1,4-galactosyltransferase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: B4GALT1, GGTB2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15291 (14-286)
      • engineered mutation (225-226)
      • engineered mutation (228)
    Domains in SCOPe 2.06: d4eema_
  • Chain 'B':
    Compound: Beta-1,4-galactosyltransferase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: B4GALT1, GGTB2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15291 (14-286)
      • engineered mutation (225-226)
      • engineered mutation (228)
    Domains in SCOPe 2.06: d4eemb_
  • Chain 'C':
    Compound: Beta-1,4-galactosyltransferase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: B4GALT1, GGTB2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15291 (14-286)
      • engineered mutation (225-226)
      • engineered mutation (228)
    Domains in SCOPe 2.06: d4eemc_
  • Heterogens: UDP, MN, SO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4eemA (A:)
asmtggqqmgrgsaslpacpeespllvgpmliefnmpvdlelvakqnpnvkmggryaprd
cvsphkvaiiipfrnrqehlkywlyylhpvlqrqqldygiyvinqagdtifnrakllnvg
fqealkdydytcfvfsdvdlipmndhnayrcfsqprhisvamdkfgfslpyvqyfggvsa
lskqqfltingfpnnywgwggedddifnrlvfrgmsisrpnavvgttrhirhsrdkknep
npqrfdriahtketmlsdglnsltyqvldvqryplytqitvdigtps

    Sequence, based on observed residues (ATOM records): (download) 
    >4eemA (A:)
slpacpeespllvgpmliefnmpvdlelvakqnpnvkmggryaprdcvsphkvaiiipfr
nrqehlkywlyylhpvlqrqqldygiyvinqagdtifnrakllnvgfqealkdydytcfv
fsdvdlipmndhnayrcfsqprhisvamdkfgfslpyvqyfggvsalskqqfltingfpn
nywgwggedddifnrlvfrgmsisrpnavvgttrhirhsrdkknepnpqrfdriahtket
mlsdglnsltyqvldvqryplytqitvdigtps

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4eemB (B:)
asmtggqqmgrgsaslpacpeespllvgpmliefnmpvdlelvakqnpnvkmggryaprd
cvsphkvaiiipfrnrqehlkywlyylhpvlqrqqldygiyvinqagdtifnrakllnvg
fqealkdydytcfvfsdvdlipmndhnayrcfsqprhisvamdkfgfslpyvqyfggvsa
lskqqfltingfpnnywgwggedddifnrlvfrgmsisrpnavvgttrhirhsrdkknep
npqrfdriahtketmlsdglnsltyqvldvqryplytqitvdigtps

    Sequence, based on observed residues (ATOM records): (download) 
    >4eemB (B:)
slpacpeespllvgpmliefnmpvdlelvakqnpnvkmggryaprdcvsphkvaiiipfr
nrqehlkywlyylhpvlqrqqldygiyvinqagdtifnrakllnvgfqealkdydytcfv
fsdvdlipmndhnayrcfsqprhisvamdkfgfslpyvqyfggvsalskqqfltingfpn
nywgwggedddifnrlvfrgmsisrpnavvgttrhirhsrdkknepnpqrfdriahtket
mlsdglnsltyqvldvqryplytqitvdigtps

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4eemC (C:)
asmtggqqmgrgsaslpacpeespllvgpmliefnmpvdlelvakqnpnvkmggryaprd
cvsphkvaiiipfrnrqehlkywlyylhpvlqrqqldygiyvinqagdtifnrakllnvg
fqealkdydytcfvfsdvdlipmndhnayrcfsqprhisvamdkfgfslpyvqyfggvsa
lskqqfltingfpnnywgwggedddifnrlvfrgmsisrpnavvgttrhirhsrdkknep
npqrfdriahtketmlsdglnsltyqvldvqryplytqitvdigtps

    Sequence, based on observed residues (ATOM records): (download) 
    >4eemC (C:)
slpacpeespllvgpmliefnmpvdlelvakqnpnvkmggryaprdcvsphkvaiiipfr
nrqehlkywlyylhpvlqrqqldygiyvinqagdtifnrakllnvgfqealkdydytcfv
fsdvdlipmndhnayrcfsqprhisvamdkfgfslpyvqyfggvsalskqqfltingfpn
nywgwggedddifnrlvfrgmsisrpnavvgttrhirhsrdkknepnpqrfdriahtket
mlsdglnsltyqvldvqryplytqitvdigtps