PDB entry 4e7e

View 4e7e on RCSB PDB site
Description: E. cloacae C115D MurA in complex with UDP-glucose
Class: transferase
Keywords: open enzyme state, cell wall, biogenesis/degradation, peptidoglycan synthesis, TRANSFERASE
Deposited on 2012-03-16, released 2013-03-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-03-20, with a file datestamp of 2013-03-15.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.198
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: UDP-N-acetylglucosamine 1-carboxyvinyltransferase
    Species: Enterobacter cloacae subsp. cloacae [TaxId:716541]
    Gene: ECL_04571, murA, murZ
    Database cross-references and differences (RAF-indexed):
    • Uniprot P33038 (0-418)
      • see remark 999 (66)
      • engineered mutation (114)
    Domains in SCOPe 2.08: d4e7ea_
  • Chain 'B':
    Compound: UDP-N-acetylglucosamine 1-carboxyvinyltransferase
    Species: Enterobacter cloacae subsp. cloacae [TaxId:716541]
    Gene: ECL_04571, murA, murZ
    Database cross-references and differences (RAF-indexed):
    • Uniprot P33038 (0-418)
      • see remark 999 (66)
      • engineered mutation (114)
    Domains in SCOPe 2.08: d4e7eb_
  • Chain 'C':
    Compound: UDP-N-acetylglucosamine 1-carboxyvinyltransferase
    Species: Enterobacter cloacae subsp. cloacae [TaxId:716541]
    Gene: ECL_04571, murA, murZ
    Database cross-references and differences (RAF-indexed):
    • Uniprot P33038 (0-418)
      • see remark 999 (66)
      • engineered mutation (114)
    Domains in SCOPe 2.08: d4e7ec_
  • Chain 'D':
    Compound: UDP-N-acetylglucosamine 1-carboxyvinyltransferase
    Species: Enterobacter cloacae subsp. cloacae [TaxId:716541]
    Gene: ECL_04571, murA, murZ
    Database cross-references and differences (RAF-indexed):
    • Uniprot P33038 (0-418)
      • see remark 999 (66)
      • engineered mutation (114)
    Domains in SCOPe 2.08: d4e7ed_
  • Heterogens: EDO, ACT, UPG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4e7eA (A:)
mdkfrvqgptrlqgevtisgaknaalpilfaallaeepveiqnvpklkdidttmklltql
gtkverdgsvwidasnvnnfsapydlvktmrasiwalgplvarfgqgqvslpggdaigar
pvdlhifgleklgaeikleegyvkasvngrlkgahivmdkvsvgatvtimsaatlaegtt
iienaarepeivdtanflvalgakisgqgtdritiegverlgggvyrvlpdrietgtflv
aaaisggkivcrnaqpdtldavlaklreagadietgedwisldmhgkrpkavtvrtaphp
afptdmqaqftllnlvaegtgvitetifenrfmhvpelirmgahaeiesntvichgvekl
sgaqvmatdlrasaslvlagciaegttvvdriyhidrgyeriedklralganiervkge

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4e7eB (B:)
mdkfrvqgptrlqgevtisgaknaalpilfaallaeepveiqnvpklkdidttmklltql
gtkverdgsvwidasnvnnfsapydlvktmrasiwalgplvarfgqgqvslpggdaigar
pvdlhifgleklgaeikleegyvkasvngrlkgahivmdkvsvgatvtimsaatlaegtt
iienaarepeivdtanflvalgakisgqgtdritiegverlgggvyrvlpdrietgtflv
aaaisggkivcrnaqpdtldavlaklreagadietgedwisldmhgkrpkavtvrtaphp
afptdmqaqftllnlvaegtgvitetifenrfmhvpelirmgahaeiesntvichgvekl
sgaqvmatdlrasaslvlagciaegttvvdriyhidrgyeriedklralganiervkge

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4e7eC (C:)
mdkfrvqgptrlqgevtisgaknaalpilfaallaeepveiqnvpklkdidttmklltql
gtkverdgsvwidasnvnnfsapydlvktmrasiwalgplvarfgqgqvslpggdaigar
pvdlhifgleklgaeikleegyvkasvngrlkgahivmdkvsvgatvtimsaatlaegtt
iienaarepeivdtanflvalgakisgqgtdritiegverlgggvyrvlpdrietgtflv
aaaisggkivcrnaqpdtldavlaklreagadietgedwisldmhgkrpkavtvrtaphp
afptdmqaqftllnlvaegtgvitetifenrfmhvpelirmgahaeiesntvichgvekl
sgaqvmatdlrasaslvlagciaegttvvdriyhidrgyeriedklralganiervkge

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4e7eD (D:)
mdkfrvqgptrlqgevtisgaknaalpilfaallaeepveiqnvpklkdidttmklltql
gtkverdgsvwidasnvnnfsapydlvktmrasiwalgplvarfgqgqvslpggdaigar
pvdlhifgleklgaeikleegyvkasvngrlkgahivmdkvsvgatvtimsaatlaegtt
iienaarepeivdtanflvalgakisgqgtdritiegverlgggvyrvlpdrietgtflv
aaaisggkivcrnaqpdtldavlaklreagadietgedwisldmhgkrpkavtvrtaphp
afptdmqaqftllnlvaegtgvitetifenrfmhvpelirmgahaeiesntvichgvekl
sgaqvmatdlrasaslvlagciaegttvvdriyhidrgyeriedklralganiervkge