PDB entry 4e3i

View 4e3i on RCSB PDB site
Description: Crystal structure of AmpC beta-lactamase in complex with a designed 3-carboxyl benzyl sulfonamide boronic acid inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: AMPC beta-lactamase, class c, hydrolase, cephalosporinase, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2012-03-09, released 2012-09-26
The last revision prior to the SCOPe 2.05 freeze date was dated 2012-11-07, with a file datestamp of 2012-11-02.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.165
AEROSPACI score: 0.61 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: Escherichia coli [TaxId:83333]
    Gene: ampA, ampC, b4150, JW4111
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4e3ia_
  • Chain 'B':
    Compound: Beta-lactamase
    Species: Escherichia coli [TaxId:83333]
    Gene: ampA, ampC, b4150, JW4111
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4e3ib_
  • Heterogens: 0N3, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4e3iA (A:)
apqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelg
svsktftgvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglplqvpd
evksssdllrfyqnwqpawapgtqrlyanssiglfgalavkpsglsfeqamqtrvfqplk
lnhtwinvppaeeknyawgyregkavhvspgaldaeaygvkstiedmarwvqsnlkpldi
nektlqqgiqlaqsrywqtgdmyqglgwemldwpvnpdsiingsdnkialaarpvkaitp
ptpavraswvhktgatggfgsyvafipekelgivmlanknypnparvdaawqilnalq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4e3iB (B:)
apqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelg
svsktftgvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglplqvpd
evksssdllrfyqnwqpawapgtqrlyanssiglfgalavkpsglsfeqamqtrvfqplk
lnhtwinvppaeeknyawgyregkavhvspgaldaeaygvkstiedmarwvqsnlkpldi
nektlqqgiqlaqsrywqtgdmyqglgwemldwpvnpdsiingsdnkialaarpvkaitp
ptpavraswvhktgatggfgsyvafipekelgivmlanknypnparvdaawqilnalq

    Sequence, based on observed residues (ATOM records): (download) 
    >4e3iB (B:)
pqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelgs
vsktftgvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglplqvpde
vksssdllrfyqnwqpawapgtqrlyanssiglfgalavkpsglsfeqamqtrvfqplkl
nhtwinvppaeeknyawgyregkavhvspgaldaeaygvkstiedmarwvqsnlkpldin
ektlqqgiqlaqsrywqtgdmyqglgwemldwpvnpdsiingsdnkialaarpvkaitpp
tpavraswvhktgatggfgsyvafipekelgivmlanknypnparvdaawqilnalq