PDB entry 4bo4

View 4bo4 on RCSB PDB site
Description: Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with N-(2-methoxyphenyl)-3,4- dihydro-2H-quinoline-1-carboxamide at 2.7A resolution
Class: oxidoreductase
Keywords: oxidoreductase, rossmann fold, fatty acid biosynthesis
Deposited on 2013-05-18, released 2013-09-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-17, with a file datestamp of 2018-01-12.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-oxoacyl-[acyl-carrier-protein] reductase FabG
    Species: PSEUDOMONAS AERUGINOSA [TaxId:208964]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54438 (22-268)
      • expression tag (20-21)
    Domains in SCOPe 2.08: d4bo4a1, d4bo4a2
  • Chain 'B':
    Compound: 3-oxoacyl-[acyl-carrier-protein] reductase FabG
    Species: PSEUDOMONAS AERUGINOSA [TaxId:208964]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54438 (22-268)
      • expression tag (16-21)
    Domains in SCOPe 2.08: d4bo4b1, d4bo4b2
  • Chain 'C':
    Compound: 3-oxoacyl-[acyl-carrier-protein] reductase FabG
    Species: PSEUDOMONAS AERUGINOSA [TaxId:208964]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54438 (22-268)
      • expression tag (2-8)
      • expression tag (16-21)
    Domains in SCOPe 2.08: d4bo4c1, d4bo4c2
  • Chain 'D':
    Compound: 3-oxoacyl-[acyl-carrier-protein] reductase FabG
    Species: PSEUDOMONAS AERUGINOSA [TaxId:208964]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54438 (22-268)
      • expression tag (17-21)
    Domains in SCOPe 2.08: d4bo4d1, d4bo4d2
  • Heterogens: 36G, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4bo4A (A:)
mhhhhhhssgvdlgtenlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtats
asgaekiaetlkangvegaglvldvssdesvaatlehiqqhlgqplivvnnagitrdnll
vrmkddewfdvvntnlnslyrlskavlrgmtkarwgriinigsvvgamgnagqtnyaaak
aglegftralarevgsraitvnavapgfidtdmtrelpeaqreallgqiplgrlgqaeei
akvvgflasdgaayvtgatvpvnggmyms

    Sequence, based on observed residues (ATOM records): (download) 
    >4bo4A (A:)
qsmslqgkvalvtgasrgigqaialelgrlgavvigtatsasgaekiaetlkangvegag
lvldvssdesvaatlehiqqhlgqplivvnnaewfdvvntnlnslyrlskavlrgmtkar
wgriinigsvvgamgnagqtnyaaakaglegftralarevgsraitvnavapgfidtdmt
relpeaqreallgqiplgrlgqaeeiakvvgflasdgaayvtgatvpvnggmyms

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4bo4B (B:)
mhhhhhhssgvdlgtenlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtats
asgaekiaetlkangvegaglvldvssdesvaatlehiqqhlgqplivvnnagitrdnll
vrmkddewfdvvntnlnslyrlskavlrgmtkarwgriinigsvvgamgnagqtnyaaak
aglegftralarevgsraitvnavapgfidtdmtrelpeaqreallgqiplgrlgqaeei
akvvgflasdgaayvtgatvpvnggmyms

    Sequence, based on observed residues (ATOM records): (download) 
    >4bo4B (B:)
nlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtatsasgaekiaetlkangv
egaglvldvssdesvaatlehiqqhlgqplivvnnadewfdvvntnlnslyrlskavlrg
mtkarwgriinigsvvgamgnagqtnyaaakaglegftralarevgsraitvnavapgfi
dtdmtrelpeaqreallgqiplgrlgqaeeiakvvgflasdgaayvtgatvpvnggmyms

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4bo4C (C:)
mhhhhhhssgvdlgtenlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtats
asgaekiaetlkangvegaglvldvssdesvaatlehiqqhlgqplivvnnagitrdnll
vrmkddewfdvvntnlnslyrlskavlrgmtkarwgriinigsvvgamgnagqtnyaaak
aglegftralarevgsraitvnavapgfidtdmtrelpeaqreallgqiplgrlgqaeei
akvvgflasdgaayvtgatvpvnggmyms

    Sequence, based on observed residues (ATOM records): (download) 
    >4bo4C (C:)
hhhhhssnlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtatsasgaekiae
tlkangvegaglvldvssdesvaatlehiqqhlgqplivvnnagitrdnllvrmkddewf
dvvntnlnslyrlskavlrgmtkarwgriinigsvvggnagqtnyaaakaglegftrala
revgsraitvnavapgfidtdmtreaqreallgqiplgrlgqaeeiakvvgflasdgaay
vtgatvpvnggmyms

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4bo4D (D:)
mhhhhhhssgvdlgtenlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtats
asgaekiaetlkangvegaglvldvssdesvaatlehiqqhlgqplivvnnagitrdnll
vrmkddewfdvvntnlnslyrlskavlrgmtkarwgriinigsvvgamgnagqtnyaaak
aglegftralarevgsraitvnavapgfidtdmtrelpeaqreallgqiplgrlgqaeei
akvvgflasdgaayvtgatvpvnggmyms

    Sequence, based on observed residues (ATOM records): (download) 
    >4bo4D (D:)
lyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtatsasgaekiaetlkangve
gaglvldvssdesvaatlehiqqhlgqplivvnnagitvrmkddewfdvvntnlnslyrl
skavlrgmtkarwgriinigsvvgamgnagqtnyaaakaglegftralarevgsraitvn
avapgfidtdmtrelpeaqreallgqiplgrlgqaeeiakvvgflasdgaayvtgatvpv
nggmyms