PDB entry 4ast

View 4ast on RCSB PDB site
Description: The apo structure of a bacterial aldo-keto reductase AKR14A1
Class: oxidoreductase
Keywords: oxidoreductase
Deposited on 2012-05-03, released 2012-05-16
The last revision prior to the SCOPe 2.02 freeze date was dated 2012-05-16, with a file datestamp of 2012-05-11.
Experiment type: XRAY
Resolution: 2.38 Å
R-factor: 0.24119
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: aldo-keto reductase akr14a1
    Species: ESCHERICHIA COLI [TaxId:469008]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d4asta_
  • Chain 'B':
    Compound: aldo-keto reductase akr14a1
    Species: ESCHERICHIA COLI [TaxId:469008]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d4astb_
  • Chain 'C':
    Compound: aldo-keto reductase akr14a1
    Species: ESCHERICHIA COLI [TaxId:469008]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d4astc_
  • Chain 'D':
    Compound: aldo-keto reductase akr14a1
    Species: ESCHERICHIA COLI [TaxId:469008]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d4astd_
  • Chain 'E':
    Compound: aldo-keto reductase akr14a1
    Species: ESCHERICHIA COLI [TaxId:469008]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d4aste_
  • Chain 'F':
    Compound: aldo-keto reductase akr14a1
    Species: ESCHERICHIA COLI [TaxId:469008]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d4astf_
  • Chain 'G':
    Compound: aldo-keto reductase akr14a1
    Species: ESCHERICHIA COLI [TaxId:469008]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d4astg_
  • Chain 'H':
    Compound: aldo-keto reductase akr14a1
    Species: ESCHERICHIA COLI [TaxId:469008]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d4asth_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4astA (A:)
mvwlanperygqmqyrycgksglrlpalslglwhnfghvnalesqrailrkafdlgithf
dlannygpppgsaeenfgrllredfaayrdeliistkagydmwpgpygsggsrkyllasl
dqslkrmgleyvdifyshrvdentpmeetasalahavqsgkalyvgissyspertqkmve
llrewkipllihqpsynllnrwvdksglldtlqnngvgciaftplaqglltgkylngipq
dsrmhregnkvrgltpkmlteanlnslrllnemaqqrgqsmaqmalswllkddrvtsvli
gasraeqleenvqalnnltfstkelaqidqhiadgelnlwqassdk

    Sequence, based on observed residues (ATOM records): (download) 
    >4astA (A:)
vwlanperygqmqyrycgksglrlpalslglwhnfghvnalesqrailrkafdlgithfd
lannygpppgsaeenfgrllredfaayrdeliistkagydmwpgpygsggsrkyllasld
qslkrmgleyvdifyshrvdentpmeetasalahavqsgkalyvgissyspertqkmvel
lrewkipllihqpsynllnrwvdksglldtlqnngvgciaftplaqglltanlnslrlln
emaqqrgqsmaqmalswllkddrvtsvligasraeqleenvqalnnltfstkelaqidqh
iadgeln

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4astB (B:)
mvwlanperygqmqyrycgksglrlpalslglwhnfghvnalesqrailrkafdlgithf
dlannygpppgsaeenfgrllredfaayrdeliistkagydmwpgpygsggsrkyllasl
dqslkrmgleyvdifyshrvdentpmeetasalahavqsgkalyvgissyspertqkmve
llrewkipllihqpsynllnrwvdksglldtlqnngvgciaftplaqglltgkylngipq
dsrmhregnkvrgltpkmlteanlnslrllnemaqqrgqsmaqmalswllkddrvtsvli
gasraeqleenvqalnnltfstkelaqidqhiadgelnlwqassdk

    Sequence, based on observed residues (ATOM records): (download) 
    >4astB (B:)
vwlanperygqmqyrycgksglrlpalslglwhnfghvnalesqrailrkafdlgithfd
lannygpppgsaeenfgrllredfaayrdeliistkagydmwpgpygsggsrkyllasld
qslkrmgleyvdifyshrvdentpmeetasalahavqsgkalyvgissyspertqkmvel
lrewkipllihqpsynllnrwvdksglldtlqnngvgciaftplaqglltglteanlnsl
rllnemaqqrgqsmaqmalswllkddrvtsvligasraeqleenvqalnnltfstkelaq
idqhiadgeln

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4astC (C:)
mvwlanperygqmqyrycgksglrlpalslglwhnfghvnalesqrailrkafdlgithf
dlannygpppgsaeenfgrllredfaayrdeliistkagydmwpgpygsggsrkyllasl
dqslkrmgleyvdifyshrvdentpmeetasalahavqsgkalyvgissyspertqkmve
llrewkipllihqpsynllnrwvdksglldtlqnngvgciaftplaqglltgkylngipq
dsrmhregnkvrgltpkmlteanlnslrllnemaqqrgqsmaqmalswllkddrvtsvli
gasraeqleenvqalnnltfstkelaqidqhiadgelnlwqassdk

    Sequence, based on observed residues (ATOM records): (download) 
    >4astC (C:)
vwlanperygqmqyrycgksglrlpalslglwhnfghvnalesqrailrkafdlgithfd
lannygpppgsaeenfgrllredfaayrdeliistkagydmwpgpygsggsrkyllasld
qslkrmgleyvdifyshrvdentpmeetasalahavqsgkalyvgissyspertqkmvel
lrewkipllihqpsynllnrwvdksglldtlqnngvgciaftplaqglltlteanlnslr
llnemaqqrgqsmaqmalswllkddrvtsvligasraeqleenvqalnnltfstkelaqi
dqhiadgeln

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4astD (D:)
mvwlanperygqmqyrycgksglrlpalslglwhnfghvnalesqrailrkafdlgithf
dlannygpppgsaeenfgrllredfaayrdeliistkagydmwpgpygsggsrkyllasl
dqslkrmgleyvdifyshrvdentpmeetasalahavqsgkalyvgissyspertqkmve
llrewkipllihqpsynllnrwvdksglldtlqnngvgciaftplaqglltgkylngipq
dsrmhregnkvrgltpkmlteanlnslrllnemaqqrgqsmaqmalswllkddrvtsvli
gasraeqleenvqalnnltfstkelaqidqhiadgelnlwqassdk

    Sequence, based on observed residues (ATOM records): (download) 
    >4astD (D:)
vwlanperygqmqyrycgksglrlpalslglwhnfghvnalesqrailrkafdlgithfd
lannygpppgsaeenfgrllredfaayrdeliistkagydmwpgpygsggsrkyllasld
qslkrmgleyvdifyshrvdentpmeetasalahavqsgkalyvgissyspertqkmvel
lrewkipllihqpsynllnrwvdksglldtlqnngvgciaftplaqglltganlnslrll
nemaqqrgqsmaqmalswllkddrvtsvligasraeqleenvqalnnltfstkelaqidq
hiadgeln

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4astE (E:)
mvwlanperygqmqyrycgksglrlpalslglwhnfghvnalesqrailrkafdlgithf
dlannygpppgsaeenfgrllredfaayrdeliistkagydmwpgpygsggsrkyllasl
dqslkrmgleyvdifyshrvdentpmeetasalahavqsgkalyvgissyspertqkmve
llrewkipllihqpsynllnrwvdksglldtlqnngvgciaftplaqglltgkylngipq
dsrmhregnkvrgltpkmlteanlnslrllnemaqqrgqsmaqmalswllkddrvtsvli
gasraeqleenvqalnnltfstkelaqidqhiadgelnlwqassdk

    Sequence, based on observed residues (ATOM records): (download) 
    >4astE (E:)
vwlanperygqmqyrycgksglrlpalslglwhnfghvnalesqrailrkafdlgithfd
lannygpppgsaeenfgrllredfaayrdeliistkagydmwpgpygsggsrkyllasld
qslkrmgleyvdifyshrvdentpmeetasalahavqsgkalyvgissyspertqkmvel
lrewkipllihqpsynllnrwvdksglldtlqnngvgciaftplaqglltlteanlnslr
llnemaqqrgqsmaqmalswllkddrvtsvligasraeqleenvqalnnltfstkelaqi
dqhiadg

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4astF (F:)
mvwlanperygqmqyrycgksglrlpalslglwhnfghvnalesqrailrkafdlgithf
dlannygpppgsaeenfgrllredfaayrdeliistkagydmwpgpygsggsrkyllasl
dqslkrmgleyvdifyshrvdentpmeetasalahavqsgkalyvgissyspertqkmve
llrewkipllihqpsynllnrwvdksglldtlqnngvgciaftplaqglltgkylngipq
dsrmhregnkvrgltpkmlteanlnslrllnemaqqrgqsmaqmalswllkddrvtsvli
gasraeqleenvqalnnltfstkelaqidqhiadgelnlwqassdk

    Sequence, based on observed residues (ATOM records): (download) 
    >4astF (F:)
vwlanperygqmqyrycgksglrlpalslglwhnfghvnalesqrailrkafdlgithfd
lannygpppgsaeenfgrllredfaayrdeliistkagydmwpgpygsggsrkyllasld
qslkrmgleyvdifyshrvdentpmeetasalahavqsgkalyvgissyspertqkmvel
lrewkipllihqpsynllnrwvdksglldtlqnngvgciaftplaqglltteanlnslrl
lnemaqqrgqsmaqmalswllkddrvtsvligasraeqleenvqalnnltfstkelaqid
qhi

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >4astG (G:)
mvwlanperygqmqyrycgksglrlpalslglwhnfghvnalesqrailrkafdlgithf
dlannygpppgsaeenfgrllredfaayrdeliistkagydmwpgpygsggsrkyllasl
dqslkrmgleyvdifyshrvdentpmeetasalahavqsgkalyvgissyspertqkmve
llrewkipllihqpsynllnrwvdksglldtlqnngvgciaftplaqglltgkylngipq
dsrmhregnkvrgltpkmlteanlnslrllnemaqqrgqsmaqmalswllkddrvtsvli
gasraeqleenvqalnnltfstkelaqidqhiadgelnlwqassdk

    Sequence, based on observed residues (ATOM records): (download) 
    >4astG (G:)
vwlanperygqmqyrycgksglrlpalslglwhnfghvnalesqrailrkafdlgithfd
lannygpppgsaeenfgrllredfaayrdeliistkagydmwpgpygsggsrkyllasld
qslkrmgleyvdifyshrvdentpmeetasalahavqsgkalyvgissyspertqkmvel
lrewkipllihqpsynllnrwvdksglldtlqnngvgciaftplaqglltnslrllnema
qqrgqsmaqmalswllkddrvtsvligasraeqleenvqalnnltfstkelaqidqhiad
gel

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4astH (H:)
mvwlanperygqmqyrycgksglrlpalslglwhnfghvnalesqrailrkafdlgithf
dlannygpppgsaeenfgrllredfaayrdeliistkagydmwpgpygsggsrkyllasl
dqslkrmgleyvdifyshrvdentpmeetasalahavqsgkalyvgissyspertqkmve
llrewkipllihqpsynllnrwvdksglldtlqnngvgciaftplaqglltgkylngipq
dsrmhregnkvrgltpkmlteanlnslrllnemaqqrgqsmaqmalswllkddrvtsvli
gasraeqleenvqalnnltfstkelaqidqhiadgelnlwqassdk

    Sequence, based on observed residues (ATOM records): (download) 
    >4astH (H:)
vwlanperygqmqyrycgksglrlpalslglwhnfghvnalesqrailrkafdlgithfd
lannygpppgsaeenfgrllredfaayrdeliistkagydmwpgpygsggsrkyllasld
qslkrmgleyvdifyshrvdentpmeetasalahavqsgkalyvgissyspertqkmvel
lrewkipllihqpsynllnrwvdksglldtlqnngvgciaftplaqglllrllnemaqqr
gqsmaqmalswllkddrvtsvligasraeqleenvqalnnltfstkelaqidqhiad