PDB entry 4ap0

View 4ap0 on RCSB PDB site
Description: The mitotic kinesin Eg5 in complex with Mg-ADP and ispinesib
Class: motor protein
Keywords: motor protein
Deposited on 2012-03-30, released 2012-09-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 2.59 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Kinesin-like protein KIF11
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4ap0a_
  • Chain 'B':
    Compound: Kinesin-like protein KIF11
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4ap0b_
  • Chain 'C':
    Compound: Kinesin-like protein KIF11
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4ap0c_
  • Chain 'D':
    Compound: Kinesin-like protein KIF11
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4ap0d_
  • Heterogens: MG, ADP, CL, G7X, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ap0A (A:)
gpmasqpnssakkkeekgkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggla
dkssrktytfdmvfgastkqidvyrsvvcpildevimgynctifaygqtgtgktftmege
rspneeytweedplagiiprtlhqifekltdngtefsvkvslleiyneelfdllnpssdv
serlqmfddprnkrgviikgleeitvhnkdevyqilekgaakrttaatlmnayssrshsv
fsvtihmkettidgeelvkigklnlvdlagsenigrsgavdkrareagninqslltlgrv
italvertphvpyreskltrilqdslggrtrtsiiatispaslnleetlstleyahrakn
ilnkpevnqk

    Sequence, based on observed residues (ATOM records): (download) 
    >4ap0A (A:)
kniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtgglsrktytfdmvfgastkqid
vyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagiiprtl
hqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgviikgle
eitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkevkigklnlvdlag
senigrinqslltlgrvitalvertphvpyreskltrilqdslggrtrtsiiatispasl
nleetlstleyahraknilnkpevn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4ap0B (B:)
gpmasqpnssakkkeekgkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggla
dkssrktytfdmvfgastkqidvyrsvvcpildevimgynctifaygqtgtgktftmege
rspneeytweedplagiiprtlhqifekltdngtefsvkvslleiyneelfdllnpssdv
serlqmfddprnkrgviikgleeitvhnkdevyqilekgaakrttaatlmnayssrshsv
fsvtihmkettidgeelvkigklnlvdlagsenigrsgavdkrareagninqslltlgrv
italvertphvpyreskltrilqdslggrtrtsiiatispaslnleetlstleyahrakn
ilnkpevnqk

    Sequence, based on observed residues (ATOM records): (download) 
    >4ap0B (B:)
niqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfdmvfgastk
qidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagiip
rtlhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprgviikgle
eitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkvkigklnlvdlags
eninqslltlgrvitalvertvpyreskltrilqdslggrtrtsiiatispaslnleetl
stleyahrakni

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4ap0C (C:)
gpmasqpnssakkkeekgkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggla
dkssrktytfdmvfgastkqidvyrsvvcpildevimgynctifaygqtgtgktftmege
rspneeytweedplagiiprtlhqifekltdngtefsvkvslleiyneelfdllnpssdv
serlqmfddprnkrgviikgleeitvhnkdevyqilekgaakrttaatlmnayssrshsv
fsvtihmkettidgeelvkigklnlvdlagsenigrsgavdkrareagninqslltlgrv
italvertphvpyreskltrilqdslggrtrtsiiatispaslnleetlstleyahrakn
ilnkpevnqk

    Sequence, based on observed residues (ATOM records): (download) 
    >4ap0C (C:)
gkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtgglkssrktytfdmvfgastk
qidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagiip
rtlhqifekltdngtefsvkvslleiyneelfdllnpssdrlqmfddprnkrgviikgle
eitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkvkigklnlvdlags
enqslltlgrvitalvepyreskltrilqdslggrtrtsiiatispaslnleetlstley
ahraknilnvn

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4ap0D (D:)
gpmasqpnssakkkeekgkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggla
dkssrktytfdmvfgastkqidvyrsvvcpildevimgynctifaygqtgtgktftmege
rspneeytweedplagiiprtlhqifekltdngtefsvkvslleiyneelfdllnpssdv
serlqmfddprnkrgviikgleeitvhnkdevyqilekgaakrttaatlmnayssrshsv
fsvtihmkettidgeelvkigklnlvdlagsenigrsgavdkrareagninqslltlgrv
italvertphvpyreskltrilqdslggrtrtsiiatispaslnleetlstleyahrakn
ilnkpevnqk

    Sequence, based on observed residues (ATOM records): (download) 
    >4ap0D (D:)
kniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtgsrktytfdmvfgastkqidvy
rsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagiiprtlhq
ifekltdngtefsvkvslleiyneelfdllnserlqmfddprnkrgviikgleeitvhnk
devyqilekgaakrttaatlmnayssrshsvfsvtihmkvkigklnlvdlagseninqsl
ltlgrvitalvehvpyreskltrilqdslggrtrtsiiatispaslnleetlstleyahr
aknilnkpe