PDB entry 4anp

View 4anp on RCSB PDB site
Description: Crystal structure of human phenylalanine hydroxylase in complex with a pharmacological chaperone
Class: oxidoreductase
Keywords: oxidoreductase, phenylketonuria, folding mechanism
Deposited on 2012-03-21, released 2012-04-11
The last revision prior to the SCOPe 2.04 freeze date was dated 2012-07-25, with a file datestamp of 2012-07-20.
Experiment type: XRAY
Resolution: 2.11 Å
R-factor: 0.20467
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phenylalanine-4-hydroxylase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4anpa_
  • Heterogens: FE, 3QI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4anpA (A:)
atvhelsrdkkkdtvpwfprtiqeldrfanqilsygaeldadhpgfkdpvyrarrkqfad
iaynyrhgqpiprveymeeekktwgtvfktlkslykthacyeynhifpllekycgfhedn
ipqledvsqflqtctgfrlrpvagllssrdflgglafrvfhctqyirhgskpmytpepdi
chellghvplfsdrsfaqfsqeiglaslgapdeyieklatiywftvefglckqgdsikay
gagllssfgelqyclsekpkllplelektaiqnytvtefqplyyvaesfndakekvrnfa
atiprpfsvrydpytqrievldnt

    Sequence, based on observed residues (ATOM records): (download) 
    >4anpA (A:)
tvpwfprtiqeldrfanqilsygaeldadhpgfkdpvyrarrkqfadiaynyrhgqpipr
veymeeekktwgtvfktlkslykthacyeynhifpllekycgfhednipqledvsqflqt
ctgfrlrpvagllssrdflgglafrvfhctqyirhgskpmytpepdichellghvplfsd
rsfaqfsqeiglaslgapdeyieklatiywftvefglckqgdsikaygagllssfgelqy
clsekpkllplelektaiqnytvtefqplyyvaesfndakekvrnfaatiprpfsvrydp
ytqrievld