PDB entry 3w2m
View 3w2m on RCSB PDB site
Description: Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-183
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: Rossmann Fold, Oxidoreductase, Dihydroorotate/orotate binding, Cytosol, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Deposited on
2012-11-30, released
2013-12-04
The last revision prior to the SCOPe 2.06 freeze date was dated
2013-12-04, with a file datestamp of
2013-11-29.
Experiment type: XRAY
Resolution: 1.58 Å
R-factor: 0.139
AEROSPACI score: 0.56
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Dihydroorotate dehydrogenase (fumarate)
Species: Trypanosoma cruzi [TaxId:353153]
Gene: PyrD
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3w2ma_ - Chain 'B':
Compound: Dihydroorotate dehydrogenase (fumarate)
Species: Trypanosoma cruzi [TaxId:353153]
Gene: PyrD
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3w2mb_ - Heterogens: ZRO, GOL, FMN, NCO, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>3w2mA (A:)
mclklnlldhvfanpfmnaagvlcsteedlrcmtasssgalvsksctsaprdgnpeprym
afplgsinsmglpnlgfdfylkyasdlhdyskkplflsisglsveenvamvrrlapvaqe
kgvllelnlscpnvpgkpqvaydfeamrtylqqvslayglpfgvkmppyfdiahfdtaaa
vlnefplvkfvtcvnsvgnglvidaesesvvikpkqgfgglggkyilptalanvnafyrr
cpdklvfgcggvysgedaflhilagasmvqvgtalqeegpgiftrledelleimarkgyr
tleefrgrvktie
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>3w2mB (B:)
mclklnlldhvfanpfmnaagvlcsteedlrcmtasssgalvsksctsaprdgnpeprym
afplgsinsmglpnlgfdfylkyasdlhdyskkplflsisglsveenvamvrrlapvaqe
kgvllelnlscpnvpgkpqvaydfeamrtylqqvslayglpfgvkmppyfdiahfdtaaa
vlnefplvkfvtcvnsvgnglvidaesesvvikpkqgfgglggkyilptalanvnafyrr
cpdklvfgcggvysgedaflhilagasmvqvgtalqeegpgiftrledelleimarkgyr
tleefrgrvktie