PDB entry 3vp1

View 3vp1 on RCSB PDB site
Description: Crystal structure of human glutaminase in complex with L-glutamate and BPTES
Class: hydrolase/hydrolase inhibitor
Keywords: HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2012-02-23, released 2012-06-13
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-06-27, with a file datestamp of 2012-06-22.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.205
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutaminase kidney isoform, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: GLS, GLS1, KIAA0838
    Database cross-references and differences (RAF-indexed):
    • Uniprot O94925 (2-End)
      • expression tag (0-1)
    Domains in SCOPe 2.06: d3vp1a1, d3vp1a2
  • Heterogens: 04A, GLU, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3vp1A (A:)
smipdfmsftshidelyesakkqsggkvadyipqlakfspdlwgvsvctvdgqrhstgdt
kvpfclqscvkplkyaiavndlgteyvhryvgkepsglrfnklflneddkphnpmvnaga
ivvtslikqgvnnaekfdyvmqflnkmagneyvgfsnatfqseresgdrnfaigyylkek
kcfpegtdmvgildfyfqlcsievtcesasvmaatlanggfcpitgervlspeavrntls
lmhscgmydfsgqfafhvglpaksgvaggillvvpnvmgmmcwsppldkmgnsvkgihfc
hdlvslcnfhnydnl

    Sequence, based on observed residues (ATOM records): (download) 
    >3vp1A (A:)
smipdfmsftshidelyesakkqsggkvadyipqlakfspdlwgvsvctvdgqrhstgdt
kvpfclqscvkplkyaiavndlgteyvhryvgkepsglrfnklflneddkphnpmvnaga
ivvtslikqgvnnaekfdyvmqflnkmagneyvgfsnatfqseresgdrnfaigyylkek
kcfpegtdmvgildfyfqlcsievtcesasvmaatlanggfcpitgervlspeavrntls
lmhscgmydfsgqfafhvglpaksgvaggillvvpnvmgmmcwsppldkmgnsvkgihfc
hdlvslcnfhnyd