PDB entry 3u0x

View 3u0x on RCSB PDB site
Description: Crystal structure of the B-specific-1,3-galactosyltransferase (GTB) in complex with compound 382
Class: transferase/transferase inhibitor
Keywords: ROSSMANN FOLD, OPEN CONFORMATION, GLYCOSYLTRANSFERASE, TRANSFERASE GTB, ABO,BLOOD GROUP ANTIGEN, GLYCOPROTEIN, METAL-BINDING, MANGANESE, UDP-GAL, H-ANTIGEN ACCEPTOR, MEMBRANE, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2011-09-29, released 2012-10-24
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-11-12, with a file datestamp of 2014-11-07.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.155
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histo-blood group ABO system transferase
    Species: Homo sapiens [TaxId:9606]
    Gene: ABO
    Database cross-references and differences (RAF-indexed):
    • Uniprot P16442 (7-End)
      • expression tag (1-6)
      • see remark 999 (178)
      • see remark 999 (209)
      • see remark 999 (211)
    Domains in SCOPe 2.05: d3u0xa_
  • Chain 'B':
    Compound: Histo-blood group ABO system transferase
    Species: Homo sapiens [TaxId:9606]
    Gene: ABO
    Database cross-references and differences (RAF-indexed):
    • Uniprot P16442 (7-End)
      • expression tag (1-6)
      • see remark 999 (178)
      • see remark 999 (209)
      • see remark 999 (211)
    Domains in SCOPe 2.05: d3u0xb_
  • Heterogens: GTI, CL, GOL, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3u0xA (A:)
maigefmvslprmvypqpkvltpcrkdvlvvtpwlapivwegtfnidilneqfrlqntti
gltvfaikkyvaflklfletaekhfmvghrvhyyvftdqpaavprvtlgtgrqlsvlevr
aykrwqdvsmrrmemisdfcerrflsevdylvcvdvdmefrdhvgveiltplfgtlhpsf
ygssreaftyerrpqsqayipkdegdfyymgaffggsvqevqrltrachqammvdqangi
eavwhdeshlnkyllrhkptkvlspeylwdqqllgwpavlrklrftavpknhqavrnp

    Sequence, based on observed residues (ATOM records): (download) 
    >3u0xA (A:)
aigefmvslprmvypqpkvltpcrkdvlvvtpwlapivwegtfnidilneqfrlqnttig
ltvfaikkyvaflklfletaekhfmvghrvhyyvftdqpaavprvtlgtgrqlsvlevwq
dvsmrrmemisdfcerrflsevdylvcvdvdmefrdhvgveiltplfgtlhpsfygssre
aftyerrpqsqayipkdegdfyymgaffggsvqevqrltrachqammvdqangieavwhd
eshlnkyllrhkptkvlspeylwdqqllgwpavlrklrftavpknhqavr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3u0xB (B:)
maigefmvslprmvypqpkvltpcrkdvlvvtpwlapivwegtfnidilneqfrlqntti
gltvfaikkyvaflklfletaekhfmvghrvhyyvftdqpaavprvtlgtgrqlsvlevr
aykrwqdvsmrrmemisdfcerrflsevdylvcvdvdmefrdhvgveiltplfgtlhpsf
ygssreaftyerrpqsqayipkdegdfyymgaffggsvqevqrltrachqammvdqangi
eavwhdeshlnkyllrhkptkvlspeylwdqqllgwpavlrklrftavpknhqavrnp

    Sequence, based on observed residues (ATOM records): (download) 
    >3u0xB (B:)
aigefmvslprmvypqpkvltpcrkdvlvvtpwlapivwegtfnidilneqfrlqnttig
ltvfaikkyvaflklfletaekhfmvghrvhyyvftdqpaavprvtlgtgrqlsvlevvs
mrrmemisdfcerrflsevdylvcvdvdmefrdhvgveiltplfgtlhpsfygssreaft
yerrpqsqayipkdegdfyymgaffggsvqevqrltrachqammvdqangieavwhdesh
lnkyllrhkptkvlspeylwdqqllgwpavlrklrftavp