PDB entry 3tu1

View 3tu1 on RCSB PDB site
Description: Exhaustive Fluorine Scanning towards Potent p53-MDM2 Antagonist
Class: ligase
Keywords: p53-binding protein Mdm2, Oncoprotein Mdm2, Double minute 2 protein, Hdm2, oncoprotein, p53, nucleus, ligase
Deposited on 2011-09-15, released 2011-11-02
The last revision prior to the SCOPe 2.01 freeze date was dated 2012-01-18, with a file datestamp of 2012-01-13.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.206
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: E3 ubiquitin-protein ligase Mdm2
    Species: Homo sapiens [TaxId:9606]
    Gene: MDM2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3tu1a_
  • Heterogens: 07G, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3tu1A (A:)
qipaseqetlvrpkplllkllksvgaqkdtytmkevlfylgqyimtkrlydekqqhivyc
sndllgdlfgvpsfsvkehrkiytmiyrnlvvvnqqessdsgtsvsen

    Sequence, based on observed residues (ATOM records): (download) 
    >3tu1A (A:)
qipaseqetlvrpkplllkllksvgaqkdtytmkevlfylgqyimtkrlydekqqhivyc
sndllgdlfgvpsfsvkehrkiytmiyrnlvvv