PDB entry 3t3c
View 3t3c on RCSB PDB site
Description: Structure of HIV PR resistant patient derived mutant (comprising 22 mutations) in complex with DRV
Class: hydrolase
Keywords: peptidase, viral particle, HYDROLASE
Deposited on
2011-07-25, released
2012-06-20
The last revision prior to the SCOPe 2.02 freeze date was dated
2012-08-22, with a file datestamp of
2012-08-17.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.184
AEROSPACI score: 0.44
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: hiv-1 protease
Species: Human immunodeficiency virus type 1 [TaxId:11686]
Gene: gag-pol
Database cross-references and differences (RAF-indexed):
- Uniprot P03367 (0-98)
- engineered mutation (3)
- engineered mutation (9)
- engineered mutation (12-13)
- engineered mutation (19)
- engineered mutation (21)
- engineered mutation (32)
- engineered mutation (34-36)
- engineered mutation (40)
- engineered mutation (42)
- engineered mutation (47)
- engineered mutation (53)
- engineered mutation (65)
- engineered mutation (68)
- engineered mutation (73)
- engineered mutation (81)
- engineered mutation (83)
- engineered mutation (88-90)
Domains in SCOPe 2.02: d3t3ca_ - Chain 'B':
Compound: hiv-1 protease
Species: Human immunodeficiency virus type 1 [TaxId:11686]
Gene: gag-pol
Database cross-references and differences (RAF-indexed):
- Uniprot P03367 (0-98)
- engineered mutation (3)
- engineered mutation (9)
- engineered mutation (12-13)
- engineered mutation (19)
- engineered mutation (21)
- engineered mutation (32)
- engineered mutation (34-36)
- engineered mutation (40)
- engineered mutation (42)
- engineered mutation (47)
- engineered mutation (53)
- engineered mutation (65)
- engineered mutation (68)
- engineered mutation (73)
- engineered mutation (81)
- engineered mutation (83)
- engineered mutation (88-90)
- Heterogens: 017, BME, SO4, HOH