PDB entry 3sjt

View 3sjt on RCSB PDB site
Description: Crystal structure of human arginase I in complex with the inhibitor Me-ABH, Resolution 1.60 A, twinned structure
Class: hydrolase/hydrolase inhibitor
Keywords: hydrolase, ABH inhibitor derivative, twinning, 2-Amino-6-borono-2-methylhexanoic acid, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2011-06-21, released 2011-07-20
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-11-16, with a file datestamp of 2011-11-11.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.13
AEROSPACI score: 0.62 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Arginase-1
    Species: Homo sapiens [TaxId:9606]
    Gene: ARG1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3sjta_
  • Chain 'B':
    Compound: Arginase-1
    Species: Homo sapiens [TaxId:9606]
    Gene: ARG1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3sjtb_
  • Heterogens: MN, 5AB, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3sjtA (A:)
msaksrtigiigapfskgqprggveegptvlrkaglleklkeqecdvkdygdlpfadipn
dspfqivknprsvgkaseqlagkvaevkkngrislvlggdhslaigsisgharvhpdlgv
iwvdahtdintpltttsgnlhgqpvsfllkelkgkipdvpgfswvtpcisakdivyiglr
dvdpgehyilktlgikyfsmtevdrlgigkvmeetlsyllgrkkrpihlsfdvdgldpsf
tpatgtpvvggltyreglyiteeiyktgllsgldimevnpslgktpeevtrtvntavait
lacfglaregnhkpidylnppk

    Sequence, based on observed residues (ATOM records): (download) 
    >3sjtA (A:)
rtigiigapfskgqprggveegptvlrkaglleklkeqecdvkdygdlpfadipndspfq
ivknprsvgkaseqlagkvaevkkngrislvlggdhslaigsisgharvhpdlgviwvda
htdintpltttsgnlhgqpvsfllkelkgkipdvpgfswvtpcisakdivyiglrdvdpg
ehyilktlgikyfsmtevdrlgigkvmeetlsyllgrkkrpihlsfdvdgldpsftpatg
tpvvggltyreglyiteeiyktgllsgldimevnpslgktpeevtrtvntavaitlacfg
laregnhkpidyl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3sjtB (B:)
msaksrtigiigapfskgqprggveegptvlrkaglleklkeqecdvkdygdlpfadipn
dspfqivknprsvgkaseqlagkvaevkkngrislvlggdhslaigsisgharvhpdlgv
iwvdahtdintpltttsgnlhgqpvsfllkelkgkipdvpgfswvtpcisakdivyiglr
dvdpgehyilktlgikyfsmtevdrlgigkvmeetlsyllgrkkrpihlsfdvdgldpsf
tpatgtpvvggltyreglyiteeiyktgllsgldimevnpslgktpeevtrtvntavait
lacfglaregnhkpidylnppk

    Sequence, based on observed residues (ATOM records): (download) 
    >3sjtB (B:)
rtigiigapfskgqprggveegptvlrkaglleklkeqecdvkdygdlpfadipndspfq
ivknprsvgkaseqlagkvaevkkngrislvlggdhslaigsisgharvhpdlgviwvda
htdintpltttsgnlhgqpvsfllkelkgkipdvpgfswvtpcisakdivyiglrdvdpg
ehyilktlgikyfsmtevdrlgigkvmeetlsyllgrkkrpihlsfdvdgldpsftpatg
tpvvggltyreglyiteeiyktgllsgldimevnpslgktpeevtrtvntavaitlacfg
laregnhkpidyl