SCOPe 2.05: Structural Classification of Proteins

PDB entry 3sio

View 3sio on RCSB PDB site
Description: Ac-AChBP ligand binding domain (not including beta 9-10 linker) mutated to human alpha-7 nAChR
Class: receptor
Keywords: Mutated Acetylcholine Binding Protein, Aplysia californica, alpha-7 human nicotinic acetylcholine receptor, AChBP, nAChR, Binding Protein, Acetylcholine, Glycosylation, RECEPTOR, Methyllycaconitine
Deposited on 2011-06-19, released 2011-10-26
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-06-26, with a file datestamp of 2013-06-21.
Experiment type: XRAY
Resolution: 2.32 Å
R-factor: 0.184
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Soluble acetylcholine receptor
Species: Aplysia californica [TaxId:6500]
Gene: AChBP
Database cross-references and differences (RAF-indexed):
- Uniprot Q8WSF8 (9-End)
  - expression tag (2-8)
  - engineered mutation (40)
  - engineered mutation (42)
  - engineered mutation (44)
  - engineered mutation (46)
  - engineered mutation (63)
  - engineered mutation (67)
  - engineered mutation (114)
  - engineered mutation (116)
  - engineered mutation (118-120)
  - engineered mutation (122)
  - engineered mutation (124-126)
  - engineered mutation (156)
  - engineered mutation (158)
  - engineered mutation (160)
Domains in SCOPe 2.05: d3sioa_
Chain 'B':
Compound: Soluble acetylcholine receptor
Species: Aplysia californica [TaxId:6500]
Gene: AChBP
Database cross-references and differences (RAF-indexed):
- Uniprot Q8WSF8 (9-End)
  - expression tag (0-8)
  - engineered mutation (40)
  - engineered mutation (42)
  - engineered mutation (44)
  - engineered mutation (46)
  - engineered mutation (63)
  - engineered mutation (67)
  - engineered mutation (114)
  - engineered mutation (116)
  - engineered mutation (118-120)
  - engineered mutation (122)
  - engineered mutation (124-126)
  - engineered mutation (156)
  - engineered mutation (158)
  - engineered mutation (160)
Domains in SCOPe 2.05: d3siob_
Chain 'C':
Compound: Soluble acetylcholine receptor
Species: Aplysia californica [TaxId:6500]
Gene: AChBP
Database cross-references and differences (RAF-indexed):
- Uniprot Q8WSF8 (9-End)
  - expression tag (4-8)
  - engineered mutation (40)
  - engineered mutation (42)
  - engineered mutation (44)
  - engineered mutation (46)
  - engineered mutation (63)
  - engineered mutation (67)
  - engineered mutation (114)
  - engineered mutation (116)
  - engineered mutation (118-120)
  - engineered mutation (122)
  - engineered mutation (124-126)
  - engineered mutation (156)
  - engineered mutation (158)
  - engineered mutation (160)
Domains in SCOPe 2.05: d3sioc_
Chain 'D':
Compound: Soluble acetylcholine receptor
Species: Aplysia californica [TaxId:6500]
Gene: AChBP
Database cross-references and differences (RAF-indexed):
- Uniprot Q8WSF8 (9-End)
  - expression tag (3-8)
  - engineered mutation (40)
  - engineered mutation (42)
  - engineered mutation (44)
  - engineered mutation (46)
  - engineered mutation (63)
  - engineered mutation (67)
  - engineered mutation (114)
  - engineered mutation (116)
  - engineered mutation (118-120)
  - engineered mutation (122)
  - engineered mutation (124-126)
  - engineered mutation (156)
  - engineered mutation (158)
  - engineered mutation (160)
Domains in SCOPe 2.05: d3siod_
Chain 'E':
Compound: Soluble acetylcholine receptor
Species: Aplysia californica [TaxId:6500]
Gene: AChBP
Database cross-references and differences (RAF-indexed):
- Uniprot Q8WSF8 (9-End)
  - expression tag (0-8)
  - engineered mutation (40)
  - engineered mutation (42)
  - engineered mutation (44)
  - engineered mutation (46)
  - engineered mutation (63)
  - engineered mutation (67)
  - engineered mutation (114)
  - engineered mutation (116)
  - engineered mutation (118-120)
  - engineered mutation (122)
  - engineered mutation (124-126)
  - engineered mutation (156)
  - engineered mutation (158)
  - engineered mutation (160)
Domains in SCOPe 2.05: d3sioe_
Chain 'F':
Compound: Soluble acetylcholine receptor
Species: Aplysia californica [TaxId:6500]
Gene: AChBP
Database cross-references and differences (RAF-indexed):
- Uniprot Q8WSF8 (9-End)
  - expression tag (2-8)
  - engineered mutation (40)
  - engineered mutation (42)
  - engineered mutation (44)
  - engineered mutation (46)
  - engineered mutation (63)
  - engineered mutation (67)
  - engineered mutation (114)
  - engineered mutation (116)
  - engineered mutation (118-120)
  - engineered mutation (122)
  - engineered mutation (124-126)
  - engineered mutation (156)
  - engineered mutation (158)
  - engineered mutation (160)
Domains in SCOPe 2.05: d3siof_
Chain 'G':
Compound: Soluble acetylcholine receptor
Species: Aplysia californica [TaxId:6500]
Gene: AChBP
Database cross-references and differences (RAF-indexed):
- Uniprot Q8WSF8 (9-End)
  - expression tag (0-8)
  - engineered mutation (40)
  - engineered mutation (42)
  - engineered mutation (44)
  - engineered mutation (46)
  - engineered mutation (63)
  - engineered mutation (67)
  - engineered mutation (114)
  - engineered mutation (116)
  - engineered mutation (118-120)
  - engineered mutation (122)
  - engineered mutation (124-126)
  - engineered mutation (156)
  - engineered mutation (158)
  - engineered mutation (160)
Domains in SCOPe 2.05: d3siog_
Chain 'H':
Compound: Soluble acetylcholine receptor
Species: Aplysia californica [TaxId:6500]
Gene: AChBP
Database cross-references and differences (RAF-indexed):
- Uniprot Q8WSF8 (9-End)
  - expression tag (4-8)
  - engineered mutation (40)
  - engineered mutation (42)
  - engineered mutation (44)
  - engineered mutation (46)
  - engineered mutation (63)
  - engineered mutation (67)
  - engineered mutation (114)
  - engineered mutation (116)
  - engineered mutation (118-120)
  - engineered mutation (122)
  - engineered mutation (124-126)
  - engineered mutation (156)
  - engineered mutation (158)
  - engineered mutation (160)
Domains in SCOPe 2.05: d3sioh_
Chain 'I':
Compound: Soluble acetylcholine receptor
Species: Aplysia californica [TaxId:6500]
Gene: AChBP
Database cross-references and differences (RAF-indexed):
- Uniprot Q8WSF8 (9-End)
  - expression tag (3-8)
  - engineered mutation (40)
  - engineered mutation (42)
  - engineered mutation (44)
  - engineered mutation (46)
  - engineered mutation (63)
  - engineered mutation (67)
  - engineered mutation (114)
  - engineered mutation (116)
  - engineered mutation (118-120)
  - engineered mutation (122)
  - engineered mutation (124-126)
  - engineered mutation (156)
  - engineered mutation (158)
  - engineered mutation (160)
Domains in SCOPe 2.05: d3sioi_
Chain 'J':
Compound: Soluble acetylcholine receptor
Species: Aplysia californica [TaxId:6500]
Gene: AChBP
Database cross-references and differences (RAF-indexed):
- Uniprot Q8WSF8 (9-End)
  - expression tag (0-8)
  - engineered mutation (40)
  - engineered mutation (42)
  - engineered mutation (44)
  - engineered mutation (46)
  - engineered mutation (63)
  - engineered mutation (67)
  - engineered mutation (114)
  - engineered mutation (116)
  - engineered mutation (118-120)
  - engineered mutation (122)
  - engineered mutation (124-126)
  - engineered mutation (156)
  - engineered mutation (158)
  - engineered mutation (160)
Domains in SCOPe 2.05: d3sioj_
Heterogens: NAG, MLK, MRD, MPD, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>3sioA (A:)
dykddddklhsqanlmrlksdlfnrspmypgptkddpltvylsfslldivkadsstnevd
lvyweqqswklnslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqnalvns
sghvqylpaqrlsfmcdptgvdseegatcavkfgswsyggweidlktdtdqvdlssyyas
skyeilsatqtrqvqhysccpepyidvnlvvkfrerragngffrnlfdsr