PDB entry 3rxx

View 3rxx on RCSB PDB site
Description: KPC-2 carbapenemase in complex with 3-NPBA
Class: hydrolase/hydrolase inhibitor
Keywords: inhibitor, beta-lactamase, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2011-05-10, released 2012-03-21
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-06-19, with a file datestamp of 2013-06-14.
Experiment type: XRAY
Resolution: 1.62 Å
R-factor: 0.162
AEROSPACI score: 0.61 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Carbepenem-hydrolyzing beta-lactamase KPC
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: bla, BLAKPC-2, kpc, kpc1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3rxxa_
  • Heterogens: NPB, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3rxxA (A:)
tnlvaepfakleqdfggsigvyamdtgsgatvsyraeerfplcssfkgflaaavlarsqq
qaglldtpirygknalvpwspisekylttgmtvaelsaaavqysdnaaanlllkelggpa
gltafmrsigdttfrldrwelelnsaipgdardtsspravteslqkltlgsalaapqrqq
fvdwlkgnttgnhriraavpadwavgdktgtcgvygtandyavvwptgrapivlavytra
pnkddkhseaviaaaarlaleglg

    Sequence, based on observed residues (ATOM records): (download) 
    >3rxxA (A:)
nlvaepfakleqdfggsigvyamdtgsgatvsyraeerfplcssfkgflaaavlarsqqq
aglldtpirygknalvpwspisekylttgmtvaelsaaavqysdnaaanlllkelggpag
ltafmrsigdttfrldrwelelnsaipgdardtsspravteslqkltlgsalaapqrqqf
vdwlkgnttgnhriraavpadwavgdktgtcgvygtandyavvwptgrapivlavytrap
nkddkhseaviaaaarlaleglg