PDB entry 3rod

View 3rod on RCSB PDB site
Description: Methyltransferase
Class: transferase
Keywords: methyltransferase, transferase
Deposited on 2011-04-25, released 2011-09-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-09-21, with a file datestamp of 2011-09-16.
Experiment type: XRAY
Resolution: 2.72 Å
R-factor: 0.208
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nicotinamide N-methyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: Nnmt
    Database cross-references and differences (RAF-indexed):
    • Uniprot P40261
      • engineered mutation (118-119)
      • engineered mutation (121)
    Domains in SCOPe 2.08: d3roda_
  • Chain 'B':
    Compound: Nicotinamide N-methyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: Nnmt
    Database cross-references and differences (RAF-indexed):
    • Uniprot P40261
      • engineered mutation (118-119)
      • engineered mutation (121)
    Domains in SCOPe 2.08: d3rodb_
  • Chain 'C':
    Compound: Nicotinamide N-methyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: Nnmt
    Database cross-references and differences (RAF-indexed):
    • Uniprot P40261
      • engineered mutation (118-119)
      • engineered mutation (121)
    Domains in SCOPe 2.08: d3rodc_
  • Chain 'D':
    Compound: Nicotinamide N-methyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: Nnmt
    Database cross-references and differences (RAF-indexed):
    • Uniprot P40261
      • engineered mutation (118-119)
      • engineered mutation (121)
    Domains in SCOPe 2.08: d3rodd_
  • Heterogens: SAH, NCA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3rodA (A:)
mgsshhhhhhssglvprgsmesgftskdtylshfnprdylekyykfgsrhsaesqilkhl
lknlfkifcldgvkgdllidigsgptiyqllsacesfkeivvtdysdqnlqelekwlkaa
paafdwspvvtyvcdlegnrvkgpekeeklrqavkqvlkcdvtqsqplgavplppadcvl
stlcldaacpdlptycralrnlgsllkpggflvimdalkssyymigeqkfsslplgreav
eaavkeagytiewfevisqsysstmanneglfslvarklsrpl

    Sequence, based on observed residues (ATOM records): (download) 
    >3rodA (A:)
sgftskdtylshfnprdylekyykfgsrhsaesqilkhllknlfkifcldgvkgdllidi
gsgptiyqllsacesfkeivvtdysdqnlqelekwlkaapaafdwspvvtyvcdlegnrv
kgpekeeklrqavkqvlkcdvtqsqplgavplppadcvlstlcldaacpdlptycralrn
lgsllkpggflvimdalkssyymigeqkfsslplgreaveaavkeagytiewfevisqsy
sstmanneglfslvarkls

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3rodB (B:)
mgsshhhhhhssglvprgsmesgftskdtylshfnprdylekyykfgsrhsaesqilkhl
lknlfkifcldgvkgdllidigsgptiyqllsacesfkeivvtdysdqnlqelekwlkaa
paafdwspvvtyvcdlegnrvkgpekeeklrqavkqvlkcdvtqsqplgavplppadcvl
stlcldaacpdlptycralrnlgsllkpggflvimdalkssyymigeqkfsslplgreav
eaavkeagytiewfevisqsysstmanneglfslvarklsrpl

    Sequence, based on observed residues (ATOM records): (download) 
    >3rodB (B:)
sgftskdtylshfnprdylekyykfgsrhsaesqilkhllknlfkifcldgvkgdllidi
gsgptiyqllsacesfkeivvtdysdqnlqelekwlkaapaafdwspvvtyvcdlegnrv
kgpekeeklrqavkqvlkcdvtqsqplgavplppadcvlstlcldaacpdlptycralrn
lgsllkpggflvimdalkssyymigeqkfsslplgreaveaavkeagytiewfevisqsy
sstmanneglfslvarkls

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3rodC (C:)
mgsshhhhhhssglvprgsmesgftskdtylshfnprdylekyykfgsrhsaesqilkhl
lknlfkifcldgvkgdllidigsgptiyqllsacesfkeivvtdysdqnlqelekwlkaa
paafdwspvvtyvcdlegnrvkgpekeeklrqavkqvlkcdvtqsqplgavplppadcvl
stlcldaacpdlptycralrnlgsllkpggflvimdalkssyymigeqkfsslplgreav
eaavkeagytiewfevisqsysstmanneglfslvarklsrpl

    Sequence, based on observed residues (ATOM records): (download) 
    >3rodC (C:)
sgftskdtylshfnprdylekyykfgsrhsaesqilkhllknlfkifcldgvkgdllidi
gsgptiyqllsacesfkeivvtdysdqnlqelekwlkaapaafdwspvvtyvcdlegnrv
kgpekeeklrqavkqvlkcdvtqsqplgavplppadcvlstlcldaacpdlptycralrn
lgsllkpggflvimdalkssyymigeqkfsslplgreaveaavkeagytiewfevisqsy
sstmanneglfslvarkls

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3rodD (D:)
mgsshhhhhhssglvprgsmesgftskdtylshfnprdylekyykfgsrhsaesqilkhl
lknlfkifcldgvkgdllidigsgptiyqllsacesfkeivvtdysdqnlqelekwlkaa
paafdwspvvtyvcdlegnrvkgpekeeklrqavkqvlkcdvtqsqplgavplppadcvl
stlcldaacpdlptycralrnlgsllkpggflvimdalkssyymigeqkfsslplgreav
eaavkeagytiewfevisqsysstmanneglfslvarklsrpl

    Sequence, based on observed residues (ATOM records): (download) 
    >3rodD (D:)
ftskdtylshfnprdylekyykfgsrhsaesqilkhllknlfkifcldgvkgdllidigs
gptiyqllsacesfkeivvtdysdqnlqelekwlkaapaafdwspvvtyvcdlegnrvkg
pekeeklrqavkqvlkcdvtqsqplgavplppadcvlstlcldaacpdlptycralrnlg
sllkpggflvimdalkssyymigeqkfsslplgreaveaavkeagytiewfevisqsyss
tmanneglfslvarkls