PDB entry 3p10

View 3p10 on RCSB PDB site
Description: Crystal structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with cytidine and FOL694, 2-(thiophen-2-yl)phenyl methanol
Class: lyase
Keywords: Seattle Structural Genomics Center for Infectious Disease, SSGCID, IspF, cytidine, FOL694, F69, MEP pathway, isoprene biosynthesis, LYASE, metal-binding
Deposited on 2010-09-29, released 2010-11-10
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-10-30, with a file datestamp of 2013-10-25.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.16
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Burkholderia pseudomallei [TaxId:320372]
    Gene: ispF, BURPS1710b_2511
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3p10a_
  • Chain 'B':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Burkholderia pseudomallei [TaxId:320372]
    Gene: ispF, BURPS1710b_2511
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3p10b_
  • Chain 'C':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Burkholderia pseudomallei [TaxId:320372]
    Gene: ispF, BURPS1710b_2511
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3p10c_
  • Heterogens: CL, ZN, CTN, F69, K, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3p10A (A:)
mahhhhhhmgtleaqtqgpgsmdfrigqgydvhqlvpgrpliiggvtipyergllghsda
dvllhaitdalfgaaalgdigrhfsdtdprfkgadsrallrecasrvaqagfairnvdst
iiaqapklaphidamraniaadldlpldrvnvkaktneklgylgrgegieaqaaalvvre
aaa

    Sequence, based on observed residues (ATOM records): (download) 
    >3p10A (A:)
mdfrigqgydvhqlvpgrpliiggvtipyergllghsdadvllhaitdalfgaaalgdig
rhfsdtdprfkgadsrallrecasrvaqagfairnvdstiiaqapklaphidamraniaa
dldlpldrvnvkaktneklgylgrgegieaqaaalvvre

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3p10B (B:)
mahhhhhhmgtleaqtqgpgsmdfrigqgydvhqlvpgrpliiggvtipyergllghsda
dvllhaitdalfgaaalgdigrhfsdtdprfkgadsrallrecasrvaqagfairnvdst
iiaqapklaphidamraniaadldlpldrvnvkaktneklgylgrgegieaqaaalvvre
aaa

    Sequence, based on observed residues (ATOM records): (download) 
    >3p10B (B:)
mdfrigqgydvhqlvpgrpliiggvtipyergllghsdadvllhaitdalfgaaalgdig
rhfsdtdprfkgadsrallrecasrvaqagfairnvdstiiaqapklaphidamraniaa
dldlpldrvnvkaktneklgylgrgegieaqaaalvvre

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3p10C (C:)
mahhhhhhmgtleaqtqgpgsmdfrigqgydvhqlvpgrpliiggvtipyergllghsda
dvllhaitdalfgaaalgdigrhfsdtdprfkgadsrallrecasrvaqagfairnvdst
iiaqapklaphidamraniaadldlpldrvnvkaktneklgylgrgegieaqaaalvvre
aaa

    Sequence, based on observed residues (ATOM records): (download) 
    >3p10C (C:)
mdfrigqgydvhqlvpgrpliiggvtipyergllghsdadvllhaitdalfgaaalgdig
rhffkgadsrallrecasrvaqagfairnvdstiiaqapklaphidamraniaadldlpl
drvnvkaktneklgylgrgegieaqaaalvvre