PDB entry 3noa
View 3noa on RCSB PDB site
Description: Crystal structure of human PPAR-gamma ligand binding domain complex with a potency improved agonist
Class: transcription
Keywords: Hypoglycemic Agents, Models, Molecular, PPAR alpha, PPAR gamma, Protein Isoforms, Quinolines, Structure-Activity Relationship, Thiazolidinediones, TRANSCRIPTION
Deposited on
2010-06-25, released
2011-06-29
The last revision prior to the SCOPe 2.04 freeze date was dated
2011-06-29, with a file datestamp of
2011-06-24.
Experiment type: XRAY
Resolution: 1.98 Å
R-factor: 0.233
AEROSPACI score: 0.42
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Peroxisome proliferator-activated receptor gamma
Species: Homo sapiens [TaxId:9606]
Gene: PPARG, NR1C3
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d3noaa_ - Chain 'B':
Compound: Peroxisome proliferator-activated receptor gamma
Species: Homo sapiens [TaxId:9606]
Gene: PPARG, NR1C3
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d3noab_ - Heterogens: 5BC, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>3noaA (A:)
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiykdly
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>3noaB (B:)
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiykdly