PDB entry 3ndt

View 3ndt on RCSB PDB site
Description: HIV-1 Protease Saquinavir:Ritonavir 1:1 complex structure
Class: hydrolase/hydrolase inhibitor
Keywords: HYDROLASE, AIDS, ASPARTYL PROTEASE, CARBAMYLATION, hydrolase-hydrolase inhibitor complex
Deposited on 2010-06-08, released 2011-07-20
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-12-07, with a file datestamp of 2011-12-02.
Experiment type: XRAY
Resolution: 1.72 Å
R-factor: 0.128
AEROSPACI score: 0.58 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protease
    Species: Human immunodeficiency virus type 1 BH10 [TaxId:11678]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03366 (0-98)
      • insertion (0)
      • engineered mutation (7)
      • engineered mutation (33)
      • engineered mutation (63)
      • engineered mutation (67)
      • engineered mutation (95)
      • engineered mutation (6)
      • engineered mutation (32)
      • engineered mutation (62)
      • engineered mutation (66)
      • engineered mutation (94)
    Domains in SCOPe 2.02: d3ndta_
  • Chain 'B':
    Compound: Protease
    Species: Human immunodeficiency virus type 1 BH10 [TaxId:11678]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03366 (0-98)
      • insertion (0)
      • engineered mutation (7)
      • engineered mutation (33)
      • engineered mutation (63)
      • engineered mutation (67)
      • engineered mutation (95)
      • engineered mutation (6)
      • engineered mutation (32)
      • engineered mutation (62)
      • engineered mutation (66)
      • engineered mutation (94)
    Domains in SCOPe 2.02: d3ndtb_
  • Chain 'C':
    Compound: Protease
    Species: Human immunodeficiency virus type 1 BH10 [TaxId:11678]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03366 (1-99)
      • insertion (1)
      • engineered mutation (8)
      • engineered mutation (34)
      • engineered mutation (64)
      • engineered mutation (68)
      • engineered mutation (96)
      • engineered mutation (7)
      • engineered mutation (33)
      • engineered mutation (63)
      • engineered mutation (67)
      • engineered mutation (95)
    Domains in SCOPe 2.02: d3ndtc_
  • Chain 'D':
    Compound: Protease
    Species: Human immunodeficiency virus type 1 BH10 [TaxId:11678]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03366 (1-99)
      • insertion (1)
      • engineered mutation (8)
      • engineered mutation (34)
      • engineered mutation (64)
      • engineered mutation (68)
      • engineered mutation (96)
      • engineered mutation (7)
      • engineered mutation (33)
      • engineered mutation (63)
      • engineered mutation (67)
      • engineered mutation (95)
    Domains in SCOPe 2.02: d3ndtd_
  • Heterogens: ROC, CL, DMS, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3ndtA (A:)
xpqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqy
dqiiieiaghkaigtvlvgptpvniigrnlltqigatlnf

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3ndtB (B:)
xpqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqy
dqiiieiaghkaigtvlvgptpvniigrnlltqigatlnf

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3ndtC (C:)
xpqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqy
dqiiieiaghkaigtvlvgptpvniigrnlltqigatlnf

    Sequence, based on observed residues (ATOM records): (download) 
    >3ndtC (C:)
pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3ndtD (D:)
xpqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqy
dqiiieiaghkaigtvlvgptpvniigrnlltqigatlnf

    Sequence, based on observed residues (ATOM records): (download) 
    >3ndtD (D:)
pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf