PDB entry 3kqn

View 3kqn on RCSB PDB site
Description: Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism
Class: hydrolase/DNA
Keywords: helicase-substrate transition-state complex, HCV, NS3 protein, helicase, DNA-binding
Deposited on 2009-11-17, released 2010-01-26
The last revision prior to the SCOPe 2.06 freeze date was dated 2010-01-26, with a file datestamp of 2010-01-22.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.19
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine protease/NTPase/helicase NS3
    Species: Hepatitis C virus [TaxId:333284]
    Gene: NS3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9WMX2 (0-435)
      • expression tag (436)
    Domains in SCOPe 2.06: d3kqna1, d3kqna2, d3kqna3
  • Chain 'E':
    Compound: 5'-d(*tp*tp*tp*tp*tp*t)-3'
  • Heterogens: BEF, ADP, MN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3kqnA (A:)
sppavpqtfqvahlhaptgsgkstkvpaayaaqgykvlvlnpsvaatlgfgaymskahgi
dpnirtgvrtittgapitystygkfladggcsggaydiiicdechstdsttilgigtvld
qaetagarlvvlatatppgsvtvphpnieevalsstgeipfygkaipietikggrhlifc
hskkkcdelaaklsglglnavayyrgldvsviptsgdvivvatdalmtgftgdfdsvidc
ntcvtqtvdfsldptftietttvpqdavsrsqrrgrtgrgrmgiyrfvtpgerpsgmfds
svlcecydagcawyeltpaetsvrlraylntpglpvcqdhlefwesvftglthidahfls
qtkqagdnfpylvayqatvcaraqapppswdqmwkclirlkptlhgptpllyrlgavqne
vttthpitkyimacmsa

  • Chain 'E':
    No sequence available.