PDB entry 3jw2

View 3jw2 on RCSB PDB site
Description: HIV-1 Protease Mutant G86S with DARUNAVIR
Class: hydrolase
Keywords: HIV-1 Protease, Mutant G86S, INHIBITOR, DARUNAVIR, AIDS, Aspartyl protease, Metal-binding, HYDROLASE
Deposited on 2009-09-17, released 2009-12-08
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.223
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Gag-Pol polyprotein
  Species: Human immunodeficiency virus type 1 (BRU ISOLATE) [TaxId:11686]
  Gene: gag-pol, Human immunodeficiency virus type 1
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367
    • engineered (6)
    • engineered (32)
    • engineered (62)
    • engineered (66)
    • engineered (85)
    • engineered (94)
  Domains in SCOPe 2.06: d3jw2a_
• Chain 'B':
  Compound: Gag-Pol polyprotein
  Species: Human immunodeficiency virus type 1 (BRU ISOLATE) [TaxId:11686]
  Gene: gag-pol, Human immunodeficiency virus type 1
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
    • engineered (6)
    • engineered (32)
    • engineered (62)
    • engineered (66)
    • engineered (85)
    • engineered (94)
  Domains in SCOPe 2.06: d3jw2b_
• Heterogens: 017, NA, CL, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3jw2A (A:)
  pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
  qiiieiaghkaigtvlvgptpvniisrnlltqigatlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3jw2B (B:)
  pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
  qiiieiaghkaigtvlvgptpvniisrnlltqigatlnf