PDB entry 3i5s

View 3i5s on RCSB PDB site
Description: Crystal structure of PI3K SH3
Class: protein binding
Keywords: SH3 domain, Alternative splicing, Disease mutation, Host-virus interaction, Phosphoprotein, Polymorphism, SH2 domain, Ubl conjugation, PROTEIN BINDING
Deposited on 2009-07-06, released 2010-03-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2010-03-02, with a file datestamp of 2010-02-26.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.243
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphatidylinositol 3-kinase regulatory subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: GRB1, PIK3R1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3i5sa_
  • Chain 'B':
    Compound: Phosphatidylinositol 3-kinase regulatory subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: GRB1, PIK3R1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3i5sb_
  • Chain 'C':
    Compound: Phosphatidylinositol 3-kinase regulatory subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: GRB1, PIK3R1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3i5sc_
  • Chain 'D':
    Compound: Phosphatidylinositol 3-kinase regulatory subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: GRB1, PIK3R1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3i5sd_
  • Heterogens: SO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3i5sA (A:)
msaegyqyralydykkereedidlhlgdiltvnkgslvalgfsdgqearpeeigwlngyn
ettgergdfpgtyveyigrkkis

    Sequence, based on observed residues (ATOM records): (download) 
    >3i5sA (A:)
egyqyralydykkereedidlhlgdiltvnkgslvalgfsdgqearpeeigwlngynett
gergdfpgtyveyigrk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3i5sB (B:)
msaegyqyralydykkereedidlhlgdiltvnkgslvalgfsdgqearpeeigwlngyn
ettgergdfpgtyveyigrkkis

    Sequence, based on observed residues (ATOM records): (download) 
    >3i5sB (B:)
egyqyralydykkereedidlhlgdiltvnkgslvalgfsdgqearpeeigwlngynett
gergdfpgtyveyigrk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3i5sC (C:)
msaegyqyralydykkereedidlhlgdiltvnkgslvalgfsdgqearpeeigwlngyn
ettgergdfpgtyveyigrkkis

    Sequence, based on observed residues (ATOM records): (download) 
    >3i5sC (C:)
egyqyralydykkereedidlhlgdiltvnkgslvalgfsdgqearpeeigwlngynett
gergdfpgtyveyigrk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3i5sD (D:)
msaegyqyralydykkereedidlhlgdiltvnkgslvalgfsdgqearpeeigwlngyn
ettgergdfpgtyveyigrkkis

    Sequence, based on observed residues (ATOM records): (download) 
    >3i5sD (D:)
egyqyralydykkereedidlhlgdiltvnkgslvalgfsdgqearpeeigwlngynett
gergdfpgtyveyigrk