PDB entry 3hun

View 3hun on RCSB PDB site
Description: Crystal structure of Penicillin binding protein 4 from Staphylococcus aureus COL in complex with Ampicillin
Class: HYDROLASE/Antibiotics
Keywords: Penicillin binding protein 4, Ampicillin, beta-lactamase, Serine type D-Ala, D-Ala-carboxypeptidase, Antibiotics
Deposited on 2009-06-15, released 2009-11-10
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-11-24, with a file datestamp of 2009-11-20.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.206
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Penicillin-binding protein 4
    Species: Staphylococcus aureus [TaxId:93062]
    Gene: PBP4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5HI26
      • engineered (210)
    Domains in SCOPe 2.05: d3huna1, d3huna2
  • Chain 'B':
    Compound: Penicillin-binding protein 4
    Species: Staphylococcus aureus [TaxId:93062]
    Gene: PBP4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5HI26
      • engineered (210)
    Domains in SCOPe 2.05: d3hunb1, d3hunb2
  • Heterogens: ZZ7, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3hunA (A:)
mgsshhhhhhssglvprgshmamknlisiiiilcltlsimtpyaqatnsdvtpvqaanqy
gyaglsaayeptsavnvsqtgqllyqynidtkwnpasmtklmtmyltleavnkgqlsldd
tvtmtnkeyimstlpelsntklypgqvwtiadllqitvsnssnaaalilakkvskntsdf
vdlmnnkakaigmknthfvnptgaensrlrsfaptkykdqertvttardyaildlhvike
tpkildftkqlaptthavtyytfnfslegakmslpgtdglktgssdtanynhtittkrgk
frinqvimgagdyknlggekqrnmmgnalmersfdqykyvkilskgeqringkkyyvend
lydvlpsdfskkdyklvvedgkvhadyprefinkdygpptvevhqpiiqkantvaksmwe
ehplftiiggtclvaglalivhmiinrlfrkrk

    Sequence, based on observed residues (ATOM records): (download) 
    >3hunA (A:)
tnsdvtpvqaanqygyaglsaayeptsavnvsqtgqllyqynidtkwnpasmtklmtmyl
tleavnkgqlslddtvtmtnkeyimstlpelsntklypgqvwtiadllqitvsnssnaaa
lilakkvskntsdfvdlmnnkakaigmknthfvnptgaensrlrsfaptkykdqertvtt
ardyaildlhviketpkildftkqlaptthavtyytfnfslegakmslpgtdglktgssd
tanynhtittkrgkfrinqvimgagdyknlggekqrnmmgnalmersfdqykyvkilskg
eqringkkyyvendlydvlpsdfskkdyklvvedgkvhadyprefinkdygpptvevhq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3hunB (B:)
mgsshhhhhhssglvprgshmamknlisiiiilcltlsimtpyaqatnsdvtpvqaanqy
gyaglsaayeptsavnvsqtgqllyqynidtkwnpasmtklmtmyltleavnkgqlsldd
tvtmtnkeyimstlpelsntklypgqvwtiadllqitvsnssnaaalilakkvskntsdf
vdlmnnkakaigmknthfvnptgaensrlrsfaptkykdqertvttardyaildlhvike
tpkildftkqlaptthavtyytfnfslegakmslpgtdglktgssdtanynhtittkrgk
frinqvimgagdyknlggekqrnmmgnalmersfdqykyvkilskgeqringkkyyvend
lydvlpsdfskkdyklvvedgkvhadyprefinkdygpptvevhqpiiqkantvaksmwe
ehplftiiggtclvaglalivhmiinrlfrkrk

    Sequence, based on observed residues (ATOM records): (download) 
    >3hunB (B:)
tnsdvtpvqaanqygyaglsaayeptsavnvsqtgqllyqynidtkwnpasmtklmtmyl
tleavnkgqlslddtvtmtnkeyimstlpelsntklypgqvwtiadllqitvsnssnaaa
lilakkvskntsdfvdlmnnkakaigmknthfvnptgaensrlrsfaptkykdqertvtt
ardyaildlhviketpkildftkqlaptthavtyytfnfslegakmslpgtdglktgssd
tanynhtittkrgkfrinqvimgagdyknlggekqrnmmgnalmersfdqykyvkilskg
eqringkkyyvendlydvlpsdfskkdyklvvedgkvhadyprefinkdygpptvevhq