PDB entry 3f92

View 3f92 on RCSB PDB site
Description: Crystal structure of ubiquitin-conjugating enzyme E2-25kDa (Huntington Interacting Protein 2) M172A mutant crystallized at pH 8.5
Class: ligase
Keywords: Ubiquitin-Conjugating, Huntington Interacting, E2-25K, Ligase, Ubiquitin-conjugating enzyme E2 K, E2(25K), Ubiquitin-protein ligase, Ubiquitin carrier protein, Huntington-interacting protein 2, HIP-2, Alternative splicing, Cytoplasm, Ubl conjugation, Ubl conjugation pathway
Deposited on 2008-11-13, released 2008-11-25
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-05-12, with a file datestamp of 2009-05-08.
Experiment type: XRAY
Resolution: 2.23 Å
R-factor: 0.174
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin-conjugating enzyme E2 K, chimera with Azorectase
    Species: Homo sapiens [TaxId:9606]
    Gene: UBE2K, HIP2, LIG
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61086 (53-252)
      • engineered (224)
      • conflict (52)
    • Uniprot A7KZT5 (Start-64)
    Domains in SCOPe 2.05: d3f92a1, d3f92a2
  • Heterogens: PG4, BME, TRS, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3f92A (A:)
mhhhhhhssglvprgsgmketaaakferqhmdspdlgtddddkamadigsefdmaniavq
rikrefkevlkseetsknqikvdlvdenftelrgeiagppdtpyeggryqleikipetyp
fnppkvrfitkiwhpnissvtgaicldilkdqwaaamtlrtvllslqallaaaepddpqd
avvanqykqnpemfkqtarlwahvyagapvsspeytkkienlcaagfdrnavivalssks
wdvetatelllsn

    Sequence, based on observed residues (ATOM records): (download) 
    >3f92A (A:)
fdmaniavqrikrefkevlkseetsknqikvdlvdenftelrgeiagppdtpyeggryql
eikipetypfnppkvrfitkiwhpnissvtgaicldilkdqwaaamtlrtvllslqalla
aaepddpqdavvanqykqnpemfkqtarlwahvyagapvsspeytkkienlcaagfdrna
vivalsskswdvetatelllsn