PDB entry 3er9

View 3er9 on RCSB PDB site
Description: Crystal structure of the heterodimeric vaccinia virus mRNA polyadenylate polymerase complex with UU and 3'-deoxy ATP
Class: Transcription, Transferase/RNA
Keywords: Polyadenylate polymerase, translocation, single tranded RNA poly(A) polymerase, RNA protein complex, processivity, heterodimer, nucleotidyltransferase, poxvirus; Methyltransferase, mRNA capping, mRNA processing, S-adenosyl-L-methionine, Transcription, Transferase, Transferase-RNA COMPLEX
Deposited on 2008-10-01, released 2009-06-16
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.06 Å
R-factor: 0.208
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase
    Species: vaccinia virus WR [TaxId:10254]
    Gene: PAPS, VACWR095, F9
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07617 (0-296)
      • engineered (139)
    Domains in SCOPe 2.01: d3er9a_
  • Chain 'B':
    Compound: Poly(A) polymerase catalytic subunit
    Species: vaccinia virus WR [TaxId:10254]
    Gene: PAPL, VACWR057, E1L
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23371 (Start-478)
      • engineered (35)
    Domains in SCOPe 2.01: d3er9b_
  • Chain 'D':
    Compound: 5'-r(up*u)-3'
  • Heterogens: GOL, 3AT, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3er9A (A:)
mdvvsldkpfmyfeeidneldyepesanevakklpyqgqlklllgelfflsklqrhgild
gatvvyigsapgthirylrdhfynlgviikwmlidgrhhdpilnglrdvtlvtrfvdeey
lrsikkqlhpskiilisdvasaaggnepstadllsnyalqnvmisilnpvasslkwrcpf
pdqwikdfyiphgnkmlqpfapsysaemrllsiytgenmrltrvtksdavnyekkmyyln
kivrnkvvvnfdypnqeydyfhmyfmlrtvycnktfpttkakvlflqqsifrflnip

    Sequence, based on observed residues (ATOM records): (download) 
    >3er9A (A:)
mdvvsldkpfmyfeeidneldyepesklpyqgqlklllgelfflsklqrhgildgatvvy
igsapgthirylrdhfynlgviikwmlidgrhhdpilnglrdvtlvtrfvdeeylrsikk
qlhpskiilisdvasgnepstadllsnyalqnvmisilnpvasslkwrcpfpdqwikdfy
iphgnkmlqpfapsysaemrllsiytgenmrltrvtksdavnyekkmyylnkivrnkvvv
nfdypnqeydyfhmyfmlrtvycnktfpttkakvlflqqsifrflnip

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3er9B (B:)
mnrnpdqntlpnitlkiietylgrvpsvneyhmlksqarniqkitvfnkdifvslvkknk
krffsdvntsaseikdrilsyfskqtqtynigklftiielqsvlvttytdilgvltikap
nvisskisynvtsmeelardmlnsmnvavidkakvmgrhnvsslvknvnklmeeylrrhn
kscicygsyslylinpnirygdidilqtnsrtflidlaflikfitgnniilskipylrny
mvikdendnhiidsfnirqdtmnvvpkifidniyivdptfqllnmikmfsqidrledlsk
dpekfnarmatmleyvrythgivfdgkrnnmpmkciidennrivtvttkdyfsfkkclvy
ldenvlssdildlnadtscdfesvtnsvylihdnimytyfsntillsdkgkvheisargl
cahillyqmltsgeykqclsdllnsmmnrdkipiyshterdkkpgrhgfiniekdiivf

    Sequence, based on observed residues (ATOM records): (download) 
    >3er9B (B:)
nitlkiietylgrvpsvneyhmlksqarniqkitvfnkdifvslvkknkkrffsdvntsa
seikdrilsyfskqtqtynigklftiielqsvlvttytdilgvltinvtsmeelardmln
smnvavvsslvknvnklmeeylrrhnkscicygsyslylinpnirygdidilqtnsrtfl
idlaflikfitgnniilskipylrnymvikdendnhiidsfnirqdtmnvvpkifidniy
ivdptfqllnmikmfsqidrledlskdpekfnarmatmleyvrythgivfdgkrnnmpmk
ciidennrivtvttkdyfsfkkclvyldenvlssdildlnadtscdfesvtnsvylihdn
imytyfsntillsdkgkvheisarglcahillyqmltsgeykqclsdllnsmmnrdkipi
yshterdkkpgrhgfiniekdiivf

  • Chain 'D':
    No sequence available.