SCOPe 2.06: Structural Classification of Proteins

PDB entry 3c06

View 3c06 on RCSB PDB site
Description: Lactobacillus CASEI Thymidylate Synthase Ternary Complex With DUMP and the Phtalimidic Derivative 14C in Multiple Binding Modes-Mode 1
Class: transferase
Keywords: METHYLTRANSFERASE, STRUCTURE-BASED DRUG DESIGN, Nucleotide biosynthesis, TRANSFERASE
Deposited on 2008-01-18, released 2009-01-20
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-07-24, with a file datestamp of 2013-07-19.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.222
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Thymidylate synthase
Species: Lactobacillus casei [TaxId:1582]
Database cross-references and differences (RAF-indexed):
- Uniprot P00469 (0-315)
Domains in SCOPe 2.06: d3c06a_
Heterogens: UMP, 14C, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>3c06A (A:)
mleqpyldlakkvldeghfkpdrthtgtysifghqmrfdlskgfpllttkkvpfglikse
llwflhgdtnirfllqhrnhiwdewafekwvksdeyhgpdmtdfghrsqkdpefaavyhe
emakfddrvlhddafaakygdlglvygsqwrawhtskgdtidqlgdvieqikthpysrrl
ivsawnpedvptmalppchtlyqfyvndgklslqlyqrsadiflgvpfniasyallthlv
ahecglevgefihtfgdahlyvnhldqikeqlsrtprpaptlqlnpdkhdifdfdmkdik
llnydpypaikapvav

Sequence, based on observed residues (ATOM records): (download)

>3c06A (A:)
mleqpyldlakkvldeghfkpdrthtgtysifghqmrfdlskgfpllttkkvpfglikse
llwflhgdtnirfllqhrnhiwdewafekwvksdeyhgppefaavyheemakfddrvlhd
dafaakygdlglvygsqwrawhtskgdtidqlgdvieqikthpysrrlivsawnpedvpt
malppchtlyqfyvndgklslqlyqrsadiflgvpfniasyallthlvahecglevgefi
htfgdahlyvnhldqikeqlsrtpraptlqlnpdkhdifdfdmkdikllnydpypaikap
vav